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Cat. No.: HY-162611

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8-Hydroxyoctanoic acid-thalidomide

8-Hydroxyoctanoic acid-thalidomide is an E3 Ligase Ligand-Linker Conjugate. 8-Hydroxyoctanoic acid-thalidomide can be used to synthesize Lw13 (HY-162589).

For research use only. We do not sell to patients.

CAS No.: 2399454-65-8
Formula: C₂₁H₂₇N₃O₅
Molecular Weight:401.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

8-Hydroxyoctanoic acid-thalidomide Chemical Structure

CAS No.: 2399454-65-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

8-Hydroxyoctanoic acid-thalidomide is an E3 Ligase Ligand-Linker Conjugate. 8-Hydroxyoctanoic acid-thalidomide can be used to synthesize Lw13 (HY-162589)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2399454-65-8
Molecular Weight 401.46
Formula C₂₁H₂₇N₃O₅
SMILES

O=C(O)CCCCCCCNC1=C2C(C(N(C3CCC(NC3=O)=O)C2)=O)=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang X, et al. Discovery of a potent and selective JAK1-targeting PROTAC degrader with anti-tumor activities. Bioorg Med Chem Lett. 2024 Sep 1;109:129838. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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References

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8-Hydroxyoctanoic acid-thalidomide

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

8-Hydroxyoctanoic acid-thalidomide Related Classifications

HY-162611 Related Classifications