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Cat. No.: HY-N2778

8-Hydroxyodoroside A

8-Hydroxyodoroside A is a Steroids product that can be isolated from the herbs of Nerium indicum.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 176519-75-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

8-Hydroxyodoroside A is a Steroids product that can be isolated from the herbs of Nerium indicum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>100 μM Compound: 10	Viability of human A549 cells by MTT assay after 24 hrs Viability of human A549 cells by MTT assay after 24 hrs	[PMID: 17595134]
A549	IC₅₀	5.9 μM Compound: 10	Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr	[PMID: 17595134]
A549	IC₅₀	6 μM Compound: 10	Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr	[PMID: 17595134]
HepG2	IC₅₀	4.7 mM Compound: 10	Growth inhibition of human HepG2 cells Growth inhibition of human HepG2 cells	[PMID: 17595134]
WI-38	IC₅₀	9.4 mM Compound: 10	Growth inhibition of human WI38 cells Growth inhibition of human WI38 cells	[PMID: 17595134]
WI-38 VA13	IC₅₀	1.6 mM Compound: 10	Growth inhibition of human VA13 cells Growth inhibition of human VA13 cells	[PMID: 17595134]

CAS No. 176519-75-8
Molecular Weight 534.68
Formula C₃₀H₄₆O₈
SMILES

O[C@@]12[C@]3([C@@](CC[C@@]1([C@@H](C4=CC(OC4)=O)CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6C[C@H]([C@H]([C@H](O6)C)O)OC)([H])CC3)C)O
Structure Classification
- Steroids
- Cardiacglycosides
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.