Amaranth (Synonyms: Acid Red 27; Azorubin S; FD & C Red Dye No. 2)

Cat. No.: HY-D0307A Purity: 99.15%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive.

For research use only. We do not sell to patients.

Amaranth Chemical Structure

CAS No. : 915-67-3

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Amaranth:

Amaranth (Standard) In-stock
Amaranth free acid Get quote

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Biological Activity
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Description

Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive^[1]^[2]^[3].

In Vivo

Amaranth (200-1000 mg/kg, p.o., twice, 24 h apart) shows no genotoxic effects in mice^[1].
Amaranth (7.5 mg/kg, p.o., 4 weeks) used at doses up to 10 times the acceptable daily intake exertes a depressing effect on the cellular but not humoral immune response in albino rats^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	6-week-old Swiss mice^[1]
Dosage:	200, 1000 mg/kg
Administration:	Oral gavage (p.o.), twice, 24 h apart
Result:	Did not increase the frequency of micronucleated colonic cells, at any dose level.

Molecular Weight

604.47

Formula

C₂₀H₁₁N₂Na₃O₁₀S₃

CAS No.

915-67-3

Appearance

Solid

Color

Brown to reddish brown

SMILES

O=S(C1=C(O)C(N=NC2=C3C=CC=CC3=C(S(=O)(O[Na])=O)C=C2)=C4C=CC(S(=O)(O[Na])=O)=CC4=C1)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (41.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 6.67 mg/mL (11.03 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6543 mL	8.2717 mL	16.5434 mL
5 mM	0.3309 mL	1.6543 mL	3.3087 mL
10 mM	0.1654 mL	0.8272 mL	1.6543 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.15%

Select Batch:

Data Sheet (280 KB) SDS (394 KB)

COA (260 KB) HNMR (290 KB) RP-HPLC (288 KB)

Handling Instructions (2659 KB)

References

[1]. Poul M, et al. Lack of genotoxic effect of food dyes amaranth, sunset yellow and tartrazine and their metabolites in the gut micronucleus assay in mice. Food Chem Toxicol. 2009 Feb;47(2):443-8. [Content Brief]

[2]. Morajkar P P, et al. Photocatalytic and microbial degradation of Amaranth dye. Avances in Biological Science Research. Academic Press, 2019: 327-345.

[3]. Hashem MM, et al. Immunological studies on Amaranth, Sunset Yellow and Curcumin as food colouring agents in albino rats. Food Chem Toxicol. 2010 Jun;48(6):1581-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	1.6543 mL	8.2717 mL	16.5434 mL	41.3585 mL
	5 mM	0.3309 mL	1.6543 mL	3.3087 mL	8.2717 mL
	10 mM	0.1654 mL	0.8272 mL	1.6543 mL	4.1359 mL
DMSO	15 mM	0.1103 mL	0.5514 mL	1.1029 mL	2.7572 mL
	20 mM	0.0827 mL	0.4136 mL	0.8272 mL	2.0679 mL
	25 mM	0.0662 mL	0.3309 mL	0.6617 mL	1.6543 mL
	30 mM	0.0551 mL	0.2757 mL	0.5514 mL	1.3786 mL
	40 mM	0.0414 mL	0.2068 mL	0.4136 mL	1.0340 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Amaranth Related Classifications

Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amaranth915-67-3Acid Red 27 Azorubin S FD & C Red Dye No. 2Acid Red27Acid Red-27Biochemical Assay ReagentsEnvironmental PollutantsEnvironmental Contaminantscellular immune responsefood additiveInhibitorinhibitorinhibit

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Amaranth (Synonyms: Acid Red 27; Azorubin S; FD & C Red Dye No. 2)

Other Forms of Amaranth:

Amaranth Related Antibodies

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•Related Small Molecules:

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Biological Activity

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References

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