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BAY-677 

Cat. No.: HY-111457
Handling Instructions

BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

For research use only. We do not sell to patients.

BAY-677 Chemical Structure

BAY-677 Chemical Structure

CAS No. : 2117404-84-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 88 In-stock
Estimated Time of Arrival: December 31
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 140 In-stock
Estimated Time of Arrival: December 31
25 mg USD 280 In-stock
Estimated Time of Arrival: December 31
50 mg USD 480 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Other Forms of BAY-677:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM[1]. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC)[2].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (124.89 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4978 mL 12.4891 mL 24.9781 mL
5 mM 0.4996 mL 2.4978 mL 4.9956 mL
10 mM 0.2498 mL 1.2489 mL 2.4978 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

400.35

Formula

C₂₀H₁₅F₃N₄O₂

CAS No.

2117404-84-7

SMILES

N#CC1=NC=C([[email protected]@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BAY-677
Cat. No.:
HY-111457
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BAY-677

Cat. No.: HY-111457