1. Metabolic Enzyme/Protease
  2. Elastase

BAY-678 racemate 

Cat. No.: HY-111515
Handling Instructions

BAY-678 racemate is a chemical probe candidate for Human Neutrophil Elastase (HNE).

For research use only. We do not sell to patients.

BAY-678 racemate Chemical Structure

BAY-678 racemate Chemical Structure

CAS No. : 675103-35-2

Size Price Stock
5 mg USD 90 Get quote
10 mg USD 140 Get quote
25 mg USD 290 Get quote

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BAY-678 racemate is a chemical probe candidate for Human Neutrophil Elastase (HNE).

Solvent & Solubility
In Vitro: 

DMSO : ≥ 150 mg/mL (374.67 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4978 mL 12.4891 mL 24.9781 mL
5 mM 0.4996 mL 2.4978 mL 4.9956 mL
10 mM 0.2498 mL 1.2489 mL 2.4978 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (6.24 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.24 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 2.5 mg/mL (6.24 mM); Clear solution; Need warming

References
Molecular Weight

400.35

Formula

C₂₀H₁₅F₃N₄O₂

CAS No.

675103-35-2

SMILES

N#CC1=NC=C(C(C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BAY-678 racemate
Cat. No.:
HY-111515
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BAY-678 racemate

Cat. No.: HY-111515