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BI-3812 

Cat. No.: HY-111381
Handling Instructions

BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.

For research use only. We do not sell to patients.

BI-3812 Chemical Structure

BI-3812 Chemical Structure

CAS No. : 2166387-64-8

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.

IC50 & Target

IC50: ≤3 nM (BCL6 BTB)[1]

In Vivo

BI-3812 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3812 shows an IC50 of 40 nM for the cellular BCL6[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7920 mL 8.9601 mL 17.9202 mL
5 mM 0.3584 mL 1.7920 mL 3.5840 mL
10 mM 0.1792 mL 0.8960 mL 1.7920 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

558.03

Formula

C₂₆H₃₂ClN₇O₅

CAS No.

2166387-64-8

SMILES

ClC1=CN=C(N2CCC(C(N(C)C)=O)CC2)N=C1NC3=CC(C=C(OCC(NC)=O)C(N4C)=O)=C4C(OC)=C3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
BI-3812
Cat. No.:
HY-111381
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BI-3812

Cat. No.: HY-111381