Bromindione
Based on 1 Customer Validation
Bromindione is a potent and long-acting, Inandione-derived, oral anticoagulant compound.
For research use only. We do not sell to patients.
- Purity: 98.25%
- CAS No.: 1146-98-1
- Formula: C15H9BrO2
- Molecular Weight:301.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1146-98-1
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Appearance Solid
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Molecular Weight 301.13
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Formula C15H9BrO2
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Color Off-white to light brown
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SMILES
O=C1C(C2=CC=C(Br)C=C2)C(C3=C1C=CC=C3)=O
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Synonyms
Fluidane; Halinone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 200 mg/mL (664.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 6.25 mg/mL (20.76 mM); Clear solution
This protocol yields a clear solution of ≥ 6.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (62.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (244 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3208 mL | 16.6041 mL | 33.2082 mL | 83.0206 mL |
| 5 mM | 0.6642 mL | 3.3208 mL | 6.6416 mL | 16.6041 mL | |
| 10 mM | 0.3321 mL | 1.6604 mL | 3.3208 mL | 8.3021 mL | |
| 15 mM | 0.2214 mL | 1.1069 mL | 2.2139 mL | 5.5347 mL | |
| 20 mM | 0.1660 mL | 0.8302 mL | 1.6604 mL | 4.1510 mL | |
| 25 mM | 0.1328 mL | 0.6642 mL | 1.3283 mL | 3.3208 mL | |
| 30 mM | 0.1107 mL | 0.5535 mL | 1.1069 mL | 2.7674 mL | |
| 40 mM | 0.0830 mL | 0.4151 mL | 0.8302 mL | 2.0755 mL | |
| 50 mM | 0.0664 mL | 0.3321 mL | 0.6642 mL | 1.6604 mL | |
| 60 mM | 0.0553 mL | 0.2767 mL | 0.5535 mL | 1.3837 mL | |
| 80 mM | 0.0415 mL | 0.2076 mL | 0.4151 mL | 1.0378 mL | |
| 100 mM | 0.0332 mL | 0.1660 mL | 0.3321 mL | 0.8302 mL |
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