13 Results for "

Chidamide

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Chidamide" in MCE Product Catalog:

36
36 Publications Verification
Art. -Nr.: HY-109015
CAS. Nr.: 1616493-44-7
Reinheit:  98.60%
Synonyms: Chidamide; HBI-8000; CS 055
Target:  

HDAC

Forschungsgebiete:  

Cancer

Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P1103
CAS. Nr.: 1030384-98-5
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
loading...
    loading...
Art. -Nr.: HY-P4070
CAS. Nr.: 1188379-43-2
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
loading...
    loading...
Art. -Nr.: HY-13592
CAS. Nr.: 743420-02-2
Synonyms: Chidamide impurity
Target:  

HDAC

Forschungsgebiete:  

Cancer

HDAC-IN-7 (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor.
loading...
    loading...
Art. -Nr.: HY-109015S
CAS. Nr.: 3078846-27-9
Synonyms: Chidamide-d4; HBI-8000-d4; CS 055-d4
Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively .
loading...
    loading...
Art. -Nr.: HY-P1103A
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
loading...
    loading...
Art. -Nr.: HY-P11293
CAS. Nr.: 1309855-53-5
Target:  

Melanocortin Receptor

Forschungsgebiete:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
loading...
    loading...
Art. -Nr.: HY-P4757
CAS. Nr.: 108081-77-2
Target:  

Parasite

Forschungsgebiete:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
loading...
    loading...
Art. -Nr.: HY-P1321
CAS. Nr.: 158859-98-4
Synonyms: 1229U91; GW1229
Forschungsgebiete:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
loading...
    loading...
Art. -Nr.: HY-109015R
CAS. Nr.: 1616493-44-7
Synonyms: Chidamide (Standard); HBI-8000 (Standard); CS 055 (Standard)
Forschungsgebiete:  

Cancer

Tucidinostat (Standard) is the analytical standard of Tucidinostat. This product is intended for research and analytical applications. Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 .
loading...
    loading...
Art. -Nr.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Forschungsgebiete:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
loading...
    loading...
Art. -Nr.: HY-183302
CAS. Nr.: 3117779-13-9
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Anticancer agent 317, a Chidamide (HY-109015) derivative, is an apoptosis inducer. Anticancer agent 317 inhibits colony formation, migration, adhesion, invasion, tumor growth, and angiogenesis. Anticancer agent 317 can be used for the research of breast cancer .
loading...
    loading...
Art. -Nr.: HY-P11480
CAS. Nr.: 3105660-96-3
Target:  

Trk Receptor

Forschungsgebiete:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
loading...
    loading...
  • 1