L-2-Aminobutyric acid
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L-2-Aminobutyric acid (H-Abu-OH) is a non-proteinogenic amino acid that exists in human tissues and body fluids. L-2-Aminobutyric acid is formed by the transamination of oxobutyric acid. L-2-Aminobutyric acid can serve as a precursor for anticonvulsant and anti-tuberculosis agents and is a key intermediate in the chemical and pharmaceutical industries.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 1492-24-6
- Formula: C4H9NO2
- Molecular Weight:103.12
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Human Endogenous Metabolite |
L-2-Aminobutyric acid is elevated in the plasma of children with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1492-24-6
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Appearance Solid
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Molecular Weight 103.12
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Formula C4H9NO2
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Color White to off-white
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SMILES
CC[C@H](N)C(O)=O
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Synonyms
H-Abu-OH
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 50 mg/mL (484.87 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (484.87 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Yudkoff M, et al. On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. Am J Clin Nutr. 1979 Feb;32(2):282-5. [Content Brief]
[2]. Xu JM, et al. Semi-Rational Engineering of Leucine Dehydrogenase for L-2-Aminobutyric Acid Production. Appl Biochem Biotechnol. 2017 Jul;182(3):898-909. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.6974 mL | 48.4872 mL | 96.9744 mL | 242.4360 mL |
| 5 mM | 1.9395 mL | 9.6974 mL | 19.3949 mL | 48.4872 mL | |
| 10 mM | 0.9697 mL | 4.8487 mL | 9.6974 mL | 24.2436 mL | |
| 15 mM | 0.6465 mL | 3.2325 mL | 6.4650 mL | 16.1624 mL | |
| 20 mM | 0.4849 mL | 2.4244 mL | 4.8487 mL | 12.1218 mL | |
| 25 mM | 0.3879 mL | 1.9395 mL | 3.8790 mL | 9.6974 mL | |
| 30 mM | 0.3232 mL | 1.6162 mL | 3.2325 mL | 8.0812 mL | |
| 40 mM | 0.2424 mL | 1.2122 mL | 2.4244 mL | 6.0609 mL | |
| 50 mM | 0.1939 mL | 0.9697 mL | 1.9395 mL | 4.8487 mL | |
| 60 mM | 0.1616 mL | 0.8081 mL | 1.6162 mL | 4.0406 mL | |
| 80 mM | 0.1212 mL | 0.6061 mL | 1.2122 mL | 3.0304 mL | |
| 100 mM | 0.0970 mL | 0.4849 mL | 0.9697 mL | 2.4244 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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