1. Metabolic Enzyme/Protease
  2. Aldose Reductase
  3. Imirestat

Imirestat (Synonyms: AL 1576; Alcon 1576; HOE 843)

Cat. No.: HY-16255 Purity: 99.52%
Handling Instructions

Imirestat (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes.

For research use only. We do not sell to patients.

Imirestat Chemical Structure

Imirestat Chemical Structure

CAS No. : 89391-50-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 1133 In-stock
Estimated Time of Arrival: December 31
1 mg USD 360 In-stock
Estimated Time of Arrival: December 31
5 mg USD 720 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1224 In-stock
Estimated Time of Arrival: December 31
20 mg USD 2160 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Description

Imirestat (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes.

In Vivo

Imirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

286.23

Formula

C₁₅H₈F₂N₂O₂

CAS No.

89391-50-4

SMILES

O=C1NC2(C(N1)=O)C3=C(C4=C2C=C(F)C=C4)C=CC(F)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (873.42 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4937 mL 17.4685 mL 34.9369 mL
5 mM 0.6987 mL 3.4937 mL 6.9874 mL
10 mM 0.3494 mL 1.7468 mL 3.4937 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

ImirestatAL 1576 Alcon 1576 HOE 843AL1576AL-1576Alcon1576Alcon 1576Alcon-1576HOE843HOE 843HOE-843Aldose ReductaseInhibitorinhibitorinhibit

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Product Name:
Imirestat
Cat. No.:
HY-16255
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