1. Immunology/Inflammation
  2. COX
  3. Pamicogrel

Pamicogrel (Synonyms: KBT3022)

Cat. No.: HY-U00175 Purity: 99.44%
Handling Instructions

Pamicogrel (KBT3022) is a cyclooxygenase (COX) inhibitor.

For research use only. We do not sell to patients.

Pamicogrel Chemical Structure

Pamicogrel Chemical Structure

CAS No. : 101001-34-7

Size Price Stock Quantity
1 mg USD 600 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1188 In-stock
Estimated Time of Arrival: December 31
10 mg USD 2088 In-stock
Estimated Time of Arrival: December 31
20 mg USD 3648 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Description

Pamicogrel (KBT3022) is a cyclooxygenase (COX) inhibitor.

IC50 & Target[1]

Cyclooxygenase

 

In Vitro

Pamicogrel is a cyclooxygenase inhibitor with platelet anti-aggregatory properties which is under development by Kanebo for chronic arterial occlusion. Pamicogrel also has potential in both prophylaxis and treatment of ischemic brain injury[1].

Molecular Weight

448.53

Formula

C₂₅H₂₄N₂O₄S

CAS No.

101001-34-7

SMILES

O=C(OCC)CN1C(C2=NC(C3=CC=C(OC)C=C3)=C(C4=CC=C(OC)C=C4)S2)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (185.78 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2295 mL 11.1475 mL 22.2951 mL
5 mM 0.4459 mL 2.2295 mL 4.4590 mL
10 mM 0.2230 mL 1.1148 mL 2.2295 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (13.93 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.44%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PamicogrelKBT3022KBT 3022KBT-3022COXCyclooxygenaseInhibitorinhibitorinhibit

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Product Name:
Pamicogrel
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HY-U00175
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