L-ANAP hydrochloride
Based on 1 Customer Validation
L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
For research use only. We do not sell to patients.
- Purity: 99.89%
- Formula: C15H17ClN2O3
- Molecular Weight:308.76
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
L-ANAP is a fluorescent, noncanonical amino acid which can be used for specific fluorescent labeling[1]. L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa). Fluorescent Uaas, including L-dansylalanine, L-(7-hydroxycoumrin-4-yl)ethylglycine and L-ANAP, are of particular interest for molecular and cellular biology, which may complement and enchance the widely used fluorescent proteins (FPs)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 308.76
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Formula C15H17ClN2O3
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Color White to yellow
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SMILES
N[C@@H](CNC1=CC=C2C=C(C(C)=O)C=CC2=C1)C(O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 33.33 mg/mL (107.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Zagotta WN, et al. Measuring distances between TRPV1 and the plasma membrane using a noncanonical amino acid and transition metal ion FRET. J Gen Physiol. 2016 Feb;147(2):201-16. [Content Brief]
[2]. Xiang Z, et al. Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid. J Org Chem. 2011 Aug 5;76(15):6367-71. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2388 mL | 16.1938 mL | 32.3876 mL | 80.9690 mL |
| 5 mM | 0.6478 mL | 3.2388 mL | 6.4775 mL | 16.1938 mL | |
| 10 mM | 0.3239 mL | 1.6194 mL | 3.2388 mL | 8.0969 mL | |
| 15 mM | 0.2159 mL | 1.0796 mL | 2.1592 mL | 5.3979 mL | |
| 20 mM | 0.1619 mL | 0.8097 mL | 1.6194 mL | 4.0485 mL | |
| 25 mM | 0.1296 mL | 0.6478 mL | 1.2955 mL | 3.2388 mL | |
| 30 mM | 0.1080 mL | 0.5398 mL | 1.0796 mL | 2.6990 mL | |
| 40 mM | 0.0810 mL | 0.4048 mL | 0.8097 mL | 2.0242 mL | |
| 50 mM | 0.0648 mL | 0.3239 mL | 0.6478 mL | 1.6194 mL | |
| 60 mM | 0.0540 mL | 0.2699 mL | 0.5398 mL | 1.3495 mL | |
| 80 mM | 0.0405 mL | 0.2024 mL | 0.4048 mL | 1.0121 mL | |
| 100 mM | 0.0324 mL | 0.1619 mL | 0.3239 mL | 0.8097 mL |