Lymecycline
Based on 1 publication(s) in Google Scholar
Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 992-21-2
- Formula: C29H38N4O10
- Molecular Weight:602.63
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Lymecycline
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Biological Activity
Bacterial[1]
Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity interfering with prokaryotic protein synthesis at the ribosome level. Lymecycline also has anti-inflammatory property[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 992-21-2
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Appearance Solid
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Molecular Weight 602.63
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Formula C29H38N4O10
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Color Yellow to brown
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SMILES
O[C@@]12[C@@]([C@@H](C(O)=C(C(NCNCCCC[C@H](N)C(O)=O)=O)C2=O)N(C)C)([H])C[C@@]3([H])C(C(C4=C(O)C=CC=C4[C@]3(O)C)=O)=C1O
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Synonyms
Mucomycin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Ethnopharmacol
Paris polyphylla Smith var. yunnanensis-derived saponins potentiate the antitumor activity of GPX4 inhibitors. [Abstract]2026 Feb 28:357:120890. PMID: 41232632
Solvent & Solubility
H2O : ≥ 100 mg/mL (165.94 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6594 mL | 8.2970 mL | 16.5939 mL | 41.4848 mL |
| 5 mM | 0.3319 mL | 1.6594 mL | 3.3188 mL | 8.2970 mL | |
| 10 mM | 0.1659 mL | 0.8297 mL | 1.6594 mL | 4.1485 mL | |
| 15 mM | 0.1106 mL | 0.5531 mL | 1.1063 mL | 2.7657 mL | |
| 20 mM | 0.0830 mL | 0.4148 mL | 0.8297 mL | 2.0742 mL | |
| 25 mM | 0.0664 mL | 0.3319 mL | 0.6638 mL | 1.6594 mL | |
| 30 mM | 0.0553 mL | 0.2766 mL | 0.5531 mL | 1.3828 mL | |
| 40 mM | 0.0415 mL | 0.2074 mL | 0.4148 mL | 1.0371 mL | |
| 50 mM | 0.0332 mL | 0.1659 mL | 0.3319 mL | 0.8297 mL | |
| 60 mM | 0.0277 mL | 0.1383 mL | 0.2766 mL | 0.6914 mL | |
| 80 mM | 0.0207 mL | 0.1037 mL | 0.2074 mL | 0.5186 mL | |
| 100 mM | 0.0166 mL | 0.0830 mL | 0.1659 mL | 0.4148 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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