- Natural Products
- Plants
- Moraceae Extract
- Humulus lupulus L.
Humulus lupulus L.
Alias: hops
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Humulus lupulus L. (33)
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- Formula: C15H24
- Molecular Weight: 204.35
(-)-α-Cadinene is a sesquiterpene hydrocarbon that can be isolated from Japanese hops. (-)-α-Cadinene is a natural product.
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- Formula: C15H26O
- Molecular Weight: 222.37
β-Caryophyllene alcohol is an active metabolite of β-caryophyllene (HY-N1415) with potent anti-asthma and anti-inflammation activity. β-Caryophyllene alcohol shows significant anti-asthmatic effect in guinea pigs. β-Caryophyllene alcohol can be used for asthma and inflammation research.
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- Formula: C26H38O4
- Molecular Weight: 414.58
Lupulone (Standard) is the analytical standard of Lupulone. This product is intended for research and analytical applications. Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
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- Formula: C21H22O5
- Molecular Weight: 354.40
7-O-Methyl-6-Prenylnaringenin is an active compound. 7-O-Methyl-6-Prenylnaringenin can be isolated from Humulus lupulus.
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- Formula: C26H38O5
- Molecular Weight: 430.58
Lupulone C (Compound 9) is an inhibitor of NO production.
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- Formula: C25H28O5
- Molecular Weight: 408.49
6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin) is a potent BCRP/ABCG2 inhibitor (IC50 = 0.410 μM) and a non-competitive allosteric PTP1B inhibitor (IC50 = 1.04 μM; Ki = 1.56 μM) that is isolated from Humulus lupulus. 6,8-Diprenylnaringenin produces non-competitive allosteric inhibition by locking the WPD catalytic loop of PTP1B in an inactive open conformation, while simultaneously binding to and inhibiting the ABCG2 drug efflux pump. 6,8-Diprenylnaringenin also exhibits antibacterial activity against MRSA (MIC = 6-13 μM) and antioxidant activity. 6,8-Diprenylnaringenin is used in research on type 2 diabetes, obesity, MRSA infection, and atherosclerosis.
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- Formula: C17H16O5
- Molecular Weight: 300.31
Flavokawin C is a natural compound with antioxidative and cytotoxicity.
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- Formula: C18H18O5
- Molecular Weight: 314.33
3'-Methylflavokawin is a Chalcones product that can be isolated from the herbs of Humulus lupulus.
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- Formula: C21H22O5
- Molecular Weight: 354.40
Isoxanthohumol (Standard) is the analytical standard of Isoxanthohumol (HY-N2584A). This product is intended for research and analytical applications. Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases.
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- Formula: C21H22O6
- Molecular Weight: 370.40
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