1. Immunology/Inflammation
  2. Aryl Hydrocarbon Receptor

PDM2 

Cat. No.: HY-112629 Purity: 98.88%
Handling Instructions

PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.

For research use only. We do not sell to patients.

PDM2 Chemical Structure

PDM2 Chemical Structure

CAS No. : 688348-25-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 160 In-stock
Estimated Time of Arrival: December 31
100 mg USD 280 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.

IC50 & Target

Ki: 1.2±0.4 nM(AhR)[1]

In Vitro

PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5263 mL 17.6317 mL 35.2634 mL
5 mM 0.7053 mL 3.5263 mL 7.0527 mL
10 mM 0.3526 mL 1.7632 mL 3.5263 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

283.58

Formula

C₁₄H₉Cl₃

CAS No.

688348-25-6

SMILES

ClC1=CC=C(/C=C/C2=CC(Cl)=CC(Cl)=C2)C=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PDM2
Cat. No.:
HY-112629
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PDM2

Cat. No.: HY-112629