1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR

PF-4778574 

Cat. No.: HY-14451
Handling Instructions

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

For research use only. We do not sell to patients.

PF-4778574 Chemical Structure

PF-4778574 Chemical Structure

CAS No. : 1219633-99-4

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

IC50 & Target

EC50: 45 to 919 nM (AMPAR)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5607 mL 12.8034 mL 25.6069 mL
5 mM 0.5121 mL 2.5607 mL 5.1214 mL
10 mM 0.2561 mL 1.2803 mL 2.5607 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

390.52

Formula

C₁₉H₂₂N₂O₃S₂

CAS No.

1219633-99-4

SMILES

O=S(N[[email protected]@H](CCOC1)[[email protected]]1C(C=C2)=CC=C2C3=CC=C(C#N)S3)(C(C)C)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
PF-4778574
Cat. No.:
HY-14451
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PF-4778574

Cat. No.: HY-14451