1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. PF-4778574

PF-4778574 

Cat. No.: HY-14451
Handling Instructions

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

For research use only. We do not sell to patients.

PF-4778574 Chemical Structure

PF-4778574 Chemical Structure

CAS No. : 1219633-99-4

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Description

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

IC50 & Target

EC50: 45 to 919 nM (AMPAR)[1]

Molecular Weight

390.52

Formula

C19H22N2O3S2

CAS No.
SMILES

O=S(N[[email protected]@H](CCOC1)[[email protected]]1C(C=C2)=CC=C2C3=CC=C(C#N)S3)(C(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PF-4778574
Cat. No.:
HY-14451
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