2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-P992089
    Telimomab 98%
    Telimomab is an anti-human monoclonal antibody targeting-CD5. Telimomab can be used for the research of immune disease.
    Telimomab
  • HY-P992090
    Altumomab 156586-92-4 98%
    Altumomab is a anti-huamn monoclonal antibody targeting CEACAM5/CEA/CD66e.
    Altumomab
  • HY-P992132
    Solaprubart 3057433-10-7 98%
    Solaprubart is a humanized IgG1-κ monoclonal antibody targeting TNFSF4/OX40L. Solaprubart regulates immune homeostasis by blocking the OX40L-OX40 signaling pathway and can be used for the research of autoimmune diseases such as atopic dermatitis.
    Solaprubart
  • HY-P992135
    Tonobafusp alfa 3037637-48-9 98%
    Tonobafusp alfa is a human immunoglobulin G4-λ targeting human MELTF. The isotype control is Human IgG4 (S228P) lambda1, Isotype Control (HY-P99987).
    Tonobafusp alfa
  • HY-P992150
    Altrakincept 98%
    Altrakincept is a recombinant hIL-4 receptor and IL-4 neutralizer. Altrakincept neutralizes endogenous IL-4, and prevents the decline of pulmonary function and acute asthma exacerbations after abrupt withdrawal of inhaled glucocorticoids.
    Altrakincept
  • HY-P992153
    Serrumab 98%
    Serrumab is a human monoclonal antibody that counteracts the biochemical and immunological effects of Tityus serrulatus venom. Serrumab inhibits the TsV-induced increase in the production of IL-6, TNFα and IL-10. Serrumab also prevents TsV-induced elevations in plasma urea, creatinine, aspartate transaminase and glucose levels, as well as the TsV-induced increase in neutrophil recruitment. Serrumab can be used in research related to envenoming by the Brazilian yellow scorpion.
    Serrumab
  • HY-P992154
    Ricefidase 98%
    Ricefidase (KJ-103) is a recombinant human immunoglobulin G-degrading enzyme. Ricefidase efficiently cleaves human IgG at the hinge region. Ricefidase rapidly reduces IgG levels. Ricefidase has low immunogenicity and clears AAV neutralizing antibodies. Ricefidase is applicable to research related to desensitization of all IgG subclasses and improvement of the suitability of AAV-based gene therapy.
    Ricefidase
  • HY-P992161
    REGN-10597 98%
    REGN-10597, composed of an anti-huPD-1-targeting antibody and IL2Ra-IL2 moiety, is a PD-1-dependent IL-2 agonist. REGN-10597 binds PD-1 to deliver masked native IL-2 to PD-1+ T cells, engaging trimeric IL-2 receptors to activate downstream signaling. REGN-10597 can be used for the research on melanoma, prostate cancer, colorectal cancer, and ovarian cancer.
    REGN-10597
  • HY-P992162
    23ME-00610 98%
    23ME-00610 is a humanized effector-function-null IgG1 antibody targeting CD200R1, with a Kd of <0.1 nM for hCD200R1. 23ME-00610 blocks the binding of CD200 to CD200R1 and inhibits the recruitment of the downstream adaptor protein DOK2 to CD200R1. 23ME-00610 restores IL-2 production suppressed by CD200. 23ME-00610 induces cytokine production in cells. 23ME-00610 enhances cell-mediated tumor cell killing in vitro. 23ME-00610 can be used for melanoma research.
    23ME-00610
  • HY-P992163
    23ME-01473 98%
    23ME-01473 is an anti-ULBP6/2/5 antibody with enhanced Fc effector function, with a Kd of 0.053 nmol/L against hULBP6, 0.23 nmol/L against hULBP2, and 1.92 nmol/L against hULBP5. 23ME-01473 restores anti-tumor immunity by activating NKG2D and FcγRIIIa. 23ME-01473 exerts anti-cancer activity in non-small cell lung cancer PDX models. 23ME-01473 can be used for the research of non-small cell lung cancer.
    23ME-01473
  • HY-P992168
    ABM101 98%
    ABM101 is a humanized monoclonal antibody targeting PD-L1.
    ABM101
  • HY-P992177
    AI-025 98%
    AI-025 is an anti-PD-1 antibody. AI-061, a combination formulation of AI-025 and ONC-392 (HY-P990042), inhibits the downregulation of cell activation and proliferation mediated by PD-1 and CTLA-4, thereby restoring immune function and activating cytotoxic T lymphocyte-mediated immune responses against tumor cells. AI-025 can be used in cancer research.
    AI-025
  • HY-P992180
    AMB8LK 98%
    AMB8LK is a human monoclonal antibody targeting H-ferritin, with specificity for tumor-associated heterologous ferritin. AMB8LK specifically recognizes and binds to H-ferritin overexpressed on the surface of tumor cells. AMB8LK can be used in research related to cancer and immune diseases.
    AMB8LK
  • HY-P992181
    AMG-329 98%
    AMG-329 (MEDI1116) is a human immunoglobulin G1λ monoclonal antibody targeting FLT3L. AMG-329 selectively binds to FLT3L, blocks FLT3L-FLT3 interaction, neutralizes soluble and cell-bound human FLT3L activity. AMG-329 reduces circulating relative proportions of plasmacytoid dendritic cells, conventional dendritic cells, and classical monocytes. AMG-329 does not induce antibody dependent cellular cytotoxicity. AMG-329 can be used for the research of sjögren’s disease.
    AMG-329
  • HY-P992182
    ANB032 98%
    ANB032 is a human IgG4 kappa BTLA agonist monoclonal antibody. ANB032 inhibits activated T cell proliferation and reduces secretion of inflammatory cytokines. ANB032 can be used for the research of atopic dermatitis[1].
    ANB032
  • HY-P992185
    Anti-ADAM17 Antibody 98%
    Anti-ADAM17 Antibody is a monoclonal antibody targeting ADAM17. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-ADAM17 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-ADAM17 Antibody
  • HY-P992186
    Anti-ADMAST4 Antibody 98%
    Anti-ADMAST4 Antibody is a monoclonal antibody targeting ADMAST4. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-ADMAST4 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-ADMAST4 Antibody
  • HY-P992187
    Anti-AGR2 Antibody 98%
    Anti-AGR2 Antibody is a monoclonal antibody that targets AGR2. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-AGR2 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-AGR2 Antibody
  • HY-P992189
    Anti-APCDD1 Antibody 98%
    Anti-APCDD1 Antibody is a monoclonal antibody that targets APCDD1. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-APCDD1 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-APCDD1 Antibody
  • HY-P992190
    Anti-Apelin Antibody 98%
    Anti-Apelin Antibody is a monoclonal antibody that targets apelin. It can be used in ELISA, FACS, and functional assays. For isotype controls of anti-Apelin Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-Apelin Antibody
Cat. No. 상품명 / Synonyms Application Reactivity