2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P991932
    Anti-CD79A Antibody 98%
    Anti-CD79A Antibody is an antibody against human CD79a. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CD79A Antibody
  • HY-P991934
    Anti-CD97 Antibody 98%
    Anti-CD97 Antibody is an antibody against human CD97.
    Anti-CD97 Antibody
  • HY-P991937
    SOL-116 98%
    SOL-116 is a humanized anti-BSSL antibody. SOL-116 blocks BSSL from binding to monocytes. SOL-116 reduces the severity of Pristane (HY-N7819)-induced arthritis in rats.
    SOL-116
  • HY-P991938
    Anti-CCR1 Antibody 98%
    Anti-CCR1 Antibody is an antibody against human CCR1/CD191. Recommend Isotype Controls:?Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Anti-CCR1 Antibody
  • HY-P991939
    Anti-CCR6 Antibody 98%
    Anti-CCR6 Antibody is an antibody against human CCR6. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CCR6 Antibody
  • HY-P991941
    ABT-182 98%
    ABT-182 is an antibody against human CCR8.
    ABT-182
  • HY-P991946
    Anti-CLDN3 Antibody 98%
    Anti-CLDN3 Antibody is an antibody against human CLDN3. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CLDN3 Antibody
  • HY-P991947
    ELB041 98%
    ELB041 (AFS98) is a rat monoclonal anti-murine c-fms antibody (IgG2a). AFS98 inhibits M-CSF–dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. AFS98 prevents development of fatty streaks in ApoE-deficient mice. ELB041 can be used for the research of atherosclerosis.
    ELB041
  • HY-P991949
    EV1007 98%
    EV1007 is a fully human antibody with a neutralizing effect on GM-CSF activity. EV1007 can be used for the research of autoimmune diseases.
    EV1007
  • HY-P991951
    ABA04 98%
    ABA04 is an antibody against human CTLA4.
    ABA04
  • HY-P991953
    BAT4706 98%
    BAT4706 is an antibody against human CTLA4. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    BAT4706
  • HY-P991954
    GT103 98%
    GT103 is a human-derived monoclonal antibody targeting complement factor H (CFH). GT103 binds to a conformationally distinct epitope of CFH on tumor cells. GT103 activates the classical complement pathway, induces complement-dependent cytotoxicity, and triggers antibody-dependent cellular phagocytosis (ADCP) of tumor cells. GT103 increases calreticulin translocation to tumor cell plasma membranes. GT103 mediates B-cell activation via Syk kinase phosphorylation. GT103 inhibits tumor growth and metastasis in animal models. GT103 can be used for the research of non-small cell lung cancer.
    GT103
  • HY-P991956
    ABB071 98%
    ABB071 is a humanized anti-CD180 monoclonal antibody. ABB071 can down-regulate the highly expressed TLR7 and IRF5 genes in systemic lupus erythematosus and induce the expression of PNPT1 and DNASE1L3 genes. ABB071 can inhibit the expression of genes related to the type I interferon pathway as well as interferon-stimulated genes (ISGs). ABB071 has anti-inflammatory activity and can reduce the levels of inflammatory cytokines. ABB071 can be used for research on systemic lupus erythematosus and psoriasis.
    ABB071
  • HY-P991959
    JMW-3B3 98%
    JMW-3B3 is a humanized IgG1λ monoclonal antibody targeting CTLA-4. JMW-3B3 selectively binds the unique C-terminal sequence of sCTLA-4 to block its immunoregulatory and immunosuppressive activity without cross-reacting with full-length CTLA-4 receptor. JMW-3B3 enhances cytokine profiles in PBMC cultures responding to lupus autoantigen-derived peptides. JMW-3B3 enhances IFN-γ production in anti-CD3 stimulated PBMC from melanoma patients at low anti-CD3 doses. JMW-3B3 can be used for the research of systemic lupus erythematosus and malignant melanoma.
    JMW-3B3
  • HY-P991996
    SM201 98%
    SM201 is a monoclonal antibody that targets FcγRIIB. SM201 specifically binds to FcγRIIB, enhances ITIM phosphorylation of FcγRIIB in an immune complex-dependent manner, and acts synergistically with immune complexes to amplify inhibitory signals. SM201 does not induce apoptosis, activate NK cells, or deplete B cells. SM201 can be used for the research of autoimmune diseases.
    SM201
  • HY-P991998
    Anti-Human/Monkey CD16a Antibody (3G8) 98%
    Anti-Human/Monkey CD16a Antibody (3G8) is a monoclonal antibody targeting CD16a. Anti-Human/Monkey CD16a Antibody (3G8) blocks FcγRIII/CD16a, upregulates the metabolic activity of CD16+ cells, downregulates CD87, a poor prognostic marker, and inhibits the engraftment and growth of leukemia cells in acute myeloid leukemia, and rapidly increases platelet counts in immune thrombocytopenia. Anti-Human/Monkey CD16a Antibody (3G8) is applicable to research related to tumor immunology.
    Anti-Human/Monkey CD16a Antibody (3G8)
  • HY-P992000
    F8-IL-4 98%
    F8-IL-4 is an immune cytokine targeting IL-4. F8-IL-4 specifically delivers IL-4 to inflammatory sites via binding to targets expressed on neovascular vessels. F8-IL-4 alleviates collagen-induced arthritis in mice by regulating T cell subsets and macrophage polarization. When combined with Dexamethasone (HY-14648), F8-IL-4 produces a synergistic and long-lasting therapeutic effect, and prevents arthritis recurrence after drug withdrawal by maintaining anti-inflammatory cell phenotypes and cytokine profiles. F8-IL-4 can be used in the research of collagen-induced arthritis.
    F8-IL-4
  • HY-P992006
    Anti-Glucagon Antibody 98%
    Anti-Glucagon Antibody is an anti-Glucagon antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Anti-Glucagon Antibody
  • HY-P992009
    Anti-GFRA4 Antibody 98%
    Anti-GFRA4 Antibody is an anti-GFRA4 antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-GFRA4 Antibody
  • HY-P992016
    Anti-NRG1 Antibody 98%
    Anti-NRG1 Antibody is an anti-NRG1 antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-NRG1 Antibody
Cat. No. Product Name / Synonyms Application Reactivity