1. Metabolic Enzyme/Protease
  2. LXR
  3. Rovazolac

Rovazolac 

Cat. No.: HY-109073 Purity: 99.82%
Handling Instructions

Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1.

For research use only. We do not sell to patients.

Rovazolac Chemical Structure

Rovazolac Chemical Structure

CAS No. : 1454288-88-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2650 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1.

IC50 & Target

Target: LXR[1]

In Vitro

Rovazolac is an anti-inflammatory drug candidate[1].

Molecular Weight

452.45

Formula

C₂₁H₁₉F₃N₂O₄S

CAS No.

1454288-88-0

SMILES

O=C(OCC)CN1C(C2=CC=C(C3=CC(S(C)(=O)=O)=CC=C3)C=C2)=CC(C(F)(F)F)=N1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 25 mg/mL (55.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2102 mL 11.0509 mL 22.1019 mL
5 mM 0.4420 mL 2.2102 mL 4.4204 mL
10 mM 0.2210 mL 1.1051 mL 2.2102 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.53 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.53 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Rovazolac
Cat. No.:
HY-109073
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