Substance P, Free Acid

Name: Substance P, Free Acid
Brand: MedChemExpress
SKU: HY-P1498
Rating: 4.5 (1 reviews)

Cat. No.: HY-P1498 Purity: 98.07%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Substance P, Free Acid Chemical Structure

CAS No. : 71977-09-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Substance P, Free Acid:

Substance P, free acid TFA In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P.

Molecular Weight

1348.61

Formula

C₆₃H₉₇N₁₇O₁₄S

CAS No.

71977-09-8

Appearance

Solid

Color

White to off-white

Sequence

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met

Sequence Shortening

RPKPQQFFGLM

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (37.08 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7415 mL	3.7075 mL	7.4150 mL
5 mM	0.1483 mL	0.7415 mL	1.4830 mL
10 mM	0.0742 mL	0.3708 mL	0.7415 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.07%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB) RP-HPLC (159 KB) MS (120 KB)

Handling Instructions (2659 KB)

References

[1]. Patel AB, et al. Substance P (free acid) adopts different conformation than native peptide in DMSO, water and DPPC bilayers. J Biomol Struct Dyn. 2001 Aug;19(1):129-38. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.7415 mL	3.7075 mL	7.4150 mL	18.5376 mL
	5 mM	0.1483 mL	0.7415 mL	1.4830 mL	3.7075 mL
	10 mM	0.0742 mL	0.3708 mL	0.7415 mL	1.8538 mL
	15 mM	0.0494 mL	0.2472 mL	0.4943 mL	1.2358 mL
	20 mM	0.0371 mL	0.1854 mL	0.3708 mL	0.9269 mL
	25 mM	0.0297 mL	0.1483 mL	0.2966 mL	0.7415 mL
	30 mM	0.0247 mL	0.1236 mL	0.2472 mL	0.6179 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.