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ADC Linkers Related Products (527)
Related Products (527)
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Dap-NE hydrochloride
0 ImagesDap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs).
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Gly-Gly-Gly-PEG2-azide
0 ImagesGly-Gly-Gly-PEG2-azide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-Carbobenzoxy-L-homoserine
0 ImagesCat. No.: HY-W025723CAS No.: 35677-88-4Synonyms: N-(Benzyloxycarbonyl)-L-homoserineN-Carbobenzoxy-L-homoserine (N-(Benzyloxycarbonyl)-L-homoserine) is L-homoserine with N-Carbobenzoxy protecting group, which can be used as a linker (ADC Linker) for the synthesis of Antibody-Drug Conjugates (ADCs).
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Ac-pSar12-OH
0 ImagesAc-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide.
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DBCO-PEG2-NHS ester
0 ImagesDBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only.
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Val-Ala-PAB
0 ImagesVal-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis.
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Azido Myristic Acid
0 ImagesAzido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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BCN-endo-PEG2-maleimide
0 ImagesBCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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FL118-C3-O-C-amide-C-NH2 formate
0 ImagesCat. No.: HY-161022AFL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..
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Fomc-Gly-Gly-Phe-Gly-OH
0 ImagesFomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.
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H-Gly-Gly-Phe-OH
0 ImagesH-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
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BCN-endo-PEG4-NHS
0 ImagesCat. No.: HY-W096079CAS No.: 1702356-19-1BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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bisSP1
0 ImagesCat. No.: HY-147325CAS No.: 2253947-15-6bisSP1 is an antibody-drug conjugate linker (ADC Linkers). bisSP1 is also a click chemistry reagent that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Dibromomaleimide-C5-COOH
0 ImagesSynonyms: DBM-C5-COOHDibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC.
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Mal-amide-PEG8-Val-Ala-PAB-PNP
0 ImagesCat. No.: HY-148425CAS No.: 2210247-59-7Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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m-PEG8-NHS ester
0 Imagesm-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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3-Azidopropanol
0 Images3-Azidopropanol is an azide-containing alcohol and a click reaction substrate. 3-Azidopropanol undergoes Cu-catalyzed addition reaction with propargyl alcohol.
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N3-TEMPO
0 ImagesN3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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18-Azido-stearic acid
0 ImagesCat. No.: HY-151692CAS No.: 1529763-58-318-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
