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ADC Linkers Related Products (527)
Related Products (527)
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2-Azidoethyl β-D-lactoside
0 ImagesCat. No.: HY-151793CAS No.: 230286-11-0beta-Lac-EO-N3 is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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CL2A TFA
0 ImagesCat. No.: HY-128945APurity: 99.87%CL2A TFA is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A TFA is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker.
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alpha-GalNAc-TEG-N3
0 Imagesalpha-GalNAc-TEG-N3 is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Me-Tet-PEG3-Maleimide
0 ImagesCat. No.: HY-156307CAS No.: 2141976-31-8Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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MDTF
0 ImagesCat. No.: HY-150043AMDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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m-PEG6-azide
0 Imagesm-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)
0 ImagesMal-EGGGG-PEG8-amide-bis(deoxyglucitol) (M67-0) is a cleavable ADC linker that can be used in the synthesis of ADCs.
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DBCO-PEG4-Val-Ala-PAB-PNP
0 ImagesCat. No.: HY-W591374CAS No.: 2348405-93-4DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.
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N-(Amino-PEG5)-N-bis(PEG4-acid)
0 ImagesN-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs).
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Boc-NMe-Val-Val-Dil-Dap-OH
0 ImagesCat. No.: HY-160795CAS No.: 1369426-99-2Boc-NMe-Val-Val-Dil-Dap-OH is a linker, that can be used for ADC synthesis.
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Spermine(N3BBB)
0 ImagesCat. No.: HY-151657CAS No.: 1190203-80-5Spermine(N3BBB) is a tri-Boc-protected azido-spermine reagent used for multi-functionalization of pseudo-glycodendrimers via click reaction.
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11-Azidoundecanoic acid
0 Images11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling. 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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NHPI-PEG4-C2-NHS ester
0 ImagesNHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs).
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Alkyne-SNAP
0 ImagesAlkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation.
