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ADC Linkers Related Products (527)
Related Products (527)
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Lys(MMT)-PAB-oxydiacetamide-PEG8-N3
0 ImagesCat. No.: HY-131157CAS No.: 1224601-12-0Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs). Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-methyltetrazine di-arm linker
0 ImagesAzido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs).
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MC-VC-PAB-NH2 TFA
0 ImagesMC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DBCO-PEG2-Val-Cit-PAB-MMAE
0 ImagesDBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism.
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Bis-sulfone-PEG3-Azide
0 ImagesCat. No.: HY-138745CAS No.: 1802908-01-5Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-sulfone-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Biotin-TEG-ATFBA
0 ImagesBiotin-TEG-ATFBA is a click chemistry reagent containing a perfluorophenylazide group. Biotin-TEG-ATFBA forms a highly stable azene intermediate that undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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4-Azidobenzyl alcohol
0 Images4-Azidobenzyl alcohol is a click chemistry reagent containing an azide group. 4-Azidobenzyl alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Alkyne-PEG5-SNAP
0 ImagesCat. No.: HY-151646Purity: 98.95%Synonyms: Alkyne-PEG5-BGAlkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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N-Butanoyl-L-homoserine lactone (Standard)
0 ImagesSynonyms: C4-HSL (Standard); N-Butyryl-L-homoserine lactone (Standard)N-Butanoyl-L-homoserine lactone (Standard) (C4-HSL (Standard)) is the analytical standard of N-Butanoyl-L-homoserine lactone (HY-114816). This product is intended for research and analytical applications. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
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BCN-exo-PEG7-maleimide
0 ImagesCat. No.: HY-134734CAS No.: 2143965-47-1BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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H-(Gly)3-Lys(N3)-OH hydrochloride
0 ImagesH-(Gly)3-Lys(N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Fmoc-Gly-NH-CH2-O-CH2COOH
0 ImagesFmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs.
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N3Ac-OPhOMe
0 ImagesCat. No.: HY-151819CAS No.: 2546513-31-7N3Ac-OPhOMe is a click chemistry reagent containing azido and p-methoxyphenyl ester groups, which can be used for biomolecule conjugation and organic synthesis.
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Fmoc-Val-Ala-aminomethyl acetate
0 ImagesCat. No.: HY-156813CAS No.: 2505045-86-1Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs.
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3,3'-(Propane-2,2-diylbis(sulfanediyl))dipropionic acid
0 ImagesCat. No.: HY-W109224CAS No.: 4265-59-23,3'-(Propane-2,2-diylbis (sulfanediyl)) dipropionic acid is a ROS-sensitive cleavable linker. 3,3'-(Propane-2,2-diylbis (sulfanediyl)) dipropionic acid is stable under physiological conditions, but undergoes cleavage in the ROS-rich tumor microenvironment, enabling the release of conjugated Camptothecin (CPT) (HY-16560). 3,3'-(Propane-2,2-diylbis (sulfanediyl)) dipropionic acid can be used in the research of cervical cancer.
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Gly-Gly-Gly-PEG3-TCO
0 ImagesGly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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MC-AAA-NHCH2OCH2COOH
0 ImagesMC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC).
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Amine-PEG3-Lys(PEG3-N3)-PEG3-N3
0 ImagesAmine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs).
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DBCO-PEG2-DBCO
0 ImagesCat. No.: HY-151834CAS No.: 2639395-48-3
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Alloc-Val-Ala-pAB
0 ImagesAlloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.
