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ADC Linkers Related Products (527)
Related Products (527)
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N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE
0 ImagesCat. No.: HY-177577CAS No.: 2892440-83-2N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE is a linker that can be synthesized to antibody-drug conjugate (ADC). N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE can be used for the study of cancer.
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Mal-amide-PEG8-Val-Cit-PAB-PNP
0 ImagesMal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker. Mal-amide-PEG8-Val-Cit-PAB-PNP consists of maleimide, a PEG spacer, Val-Cit dipeptide, PAB and PNP carbonate, and is applicable for the synthesis of ADCs.
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Biotin-PEG4-MeTz
0 ImagesCat. No.: HY-151741CAS No.: 1962919-31-8Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates.
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SC209 intermediate-1
0 ImagesCat. No.: HY-47968CAS No.: 1977557-93-9SC209 intermediate-1 (Compound A7a) is an ADC linker. SC209 intermediate-1 can be used for synthesis of ADCs.
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DBCO-N-bis(PEG4-NHS ester)
0 ImagesCat. No.: HY-145090CAS No.: 2639395-38-1DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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(2S)-N3-IsoSer (DCHA)
0 ImagesCat. No.: HY-151702APurity: 98.29%(2S)-N3-IsoSer DCHA is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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(S)-N3-HABA (DCHA)
0 ImagesCat. No.: HY-151866A(S)-N3-HABA (DCHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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2-MSP-C3-NHS ester
0 Images2-MSP-C3-NHS ester is a linker that can be used in the synthesis of ADCs.
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N3-Gly-Gly-Gly-OH
0 ImagesCat. No.: HY-151746CAS No.: 1993176-75-2N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Fmoc-Gly-Gly-OSu
0 ImagesFmoc-Gly-Gly-OSu is a dipeptide linker intermediate composed of glycine residues, with its N-terminus protected by Fmoc and C-terminus activated by N-hydroxysuccinimide (OSu). Fmoc-Gly-Gly-OSu can be used for the synthesis of ADC linker.
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Boc-Gly-Gly-NHS ester
0 ImagesCat. No.: HY-W800659CAS No.: 29248-48-4Boc-Gly-Gly-NHS ester can be used to selectively attach small molecules to specific amino acid residues on proteins, creating conjugates that can be used for a variety of applications in drug discovery and diagnostic assays.
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Allyl (2-aminoethyl)carbamate hydrochloride
0 ImagesCat. No.: HY-W098764CAS No.: 1049722-41-9Allyl (2-aminoethyl)carbamate hydrochloride is a cleavable linker.
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Dap-NE hydrochloride (GMP)
0 ImagesCat. No.: HY-78932GCAS No.: 2019182-02-4Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs).
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Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me
0 ImagesCat. No.: HY-180467CAS No.: 2823367-76-4Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me (Compound G12) is a disaccharide linker. Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me can be efficiently recognized by the endo-glycosidase Endo-S2 and can be directedly transferred to the conserved N-glycosylation site (Asn297 position) of the antibody's Fc domain through enzymatic catalytic reactions, thereby achieving site-specific modification of the antibody. Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me can be used for for the synthesis of antibody-conjugated drugs (ADCs).
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Gly-Gly-Phe-Gly
0 ImagesGly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689).
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NH2-MPAA-NODA
0 ImagesCat. No.: HY-135859CAS No.: 2705545-44-2NH2-MPAA-NODA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone. NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.
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Fmoc-DAP-N3
0 ImagesFmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Allyl (2-aminoethyl)carbamate
0 ImagesAllyl (2-aminoethyl)carbamate is a cleavable linker.
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SCO-PEG3-NH2 formate
0 ImagesCat. No.: HY-156316ASCO-PEG3-NH2 formate is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-NH2 formate can be used as a copper-free click chemical reagent for catalyst-free click reactions.
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vc-PABC-DM1
0 Imagesvc-PABC-DM1 used to synthesize an ADC molecule based on utilize disulfide linker. vc-PABC-DM1 can be used to explore serum stability.
