2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. BCRP
  5. BCRP Substrate

BCRP Substrate

BCRP Substrates (2):

Cat. No. Product Name Effect Purity
  • HY-D3179
    CDg13
    		Substrate
    CDg13 is a fluorescent probe that specifically detects living neural stem/progenitor cells. CDg13 localizes to the endoplasmic reticulum via its dihexyl moiety, with no interaction with endoplasmic reticulum biomolecules. CDg13 undergoes selective efflux by active ABCG2 transporters, with increased intracellular accumulation following ABCG2 inhibition or knockdown. CDg13 isolates and enriches self-renewable neural stem/progenitor cells from embryonic mouse brain tissue, stains neural stem/progenitor cells brightly, and sorts ABCG2low cell populations from heterogeneous populations. (Ex/Em = 520/553 nm)
  • HY-172233
    INCB-056868
    		Substrate
    INCB-056868 is the metabolite M11 of Epacadostat (HY-15689). INCB-056868 can also serve as a substrate for BCRP. INCB-056868 is promising for research of metabolic diseases.