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Ceftezole
0 ImagesCat. No.: HY-N7095CAS No.: 26973-24-0Synonyms: CTZCeftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. -
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D-Arabinopyranose-13C5
0 ImagesCat. No.: HY-N7082SPurity: 99.9%D-Arabinopyranose-13C5 is the 13C-labeled D-Arabinopyranose (HY-N7082). D-Arabinpyranose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinpyranose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinpyranose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinpyranose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinpyranose is the ring-opened form of the aldopentose D-Arabinpyranose (HY-N7082). -
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Brevinin-1
0 ImagesCat. No.: HY-P5659CAS No.: 145963-49-1Brevinin-1 is an antimicrobial peptide derived from the skin secretions of Rana esculenta. -
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Bombinin-like peptide 3
0 ImagesCat. No.: HY-P5634CAS No.: 138220-02-7Synonyms: BLP-3Bombinin-like peptide 3 is an antimicrobial peptide derived from skin secretions of asian toad Bombina orientalis. -
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Glicophenone
0 ImagesCat. No.: HY-142097CAS No.: 303175-66-8Glicophenone is an antibacterial agent with MICs of both 32 μg/mL against MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623 and MSSA 209P. -
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Urease-IN-11
0 ImagesCat. No.: HY-162139CAS No.: 517906-12-6Urease-IN-11 (Compound 6e) is a competitive urease inhibitor (IC50)=10.41 µM). Urease-IN-11 can be used to study diseases such as urease-related gastritis and peptic ulcer. -
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DRGN-1
0 ImagesCat. No.: HY-P11165CAS No.: 2173394-02-8DRGN-1 is an antimicrobial peptide. DRGN-1 exhibits potent antimicrobial and anti-biofilm activities, inhibiting both Gram-negative and Gram-positive bacteria, with an EC50 range of 0.50-4.62 μM. DRGN-1 exerts its antimicrobial effect by disrupting bacterial membrane permeability and slightly depolarizing the membrane potential. DRGN-1 inhibits the formation of biofilms of single bacterial species and mixed species of Pseudomonas aeruginosa and Staphylococcus aureus. DRGN-1 can significantly promote the healing of uninfected and mixed biofilm-infected mouse wounds. DRGN-1 can be used for the study of infections. -
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3-Methyl-chuangxinmycin
0 ImagesCat. No.: HY-1628613-Methyl-chuangxinmycin is an antibiotic. 3-Methyl-chuangxinmycin can affect the translation process in bacteria and mammalian cells by inhibiting the enzyme that synthesizes tryptophan tRNA (TrpRS). 3-Methyl-chuangxinmycin can downregulate genes related to interferon, TNF, and inflammatory responses in RDEB_L1 cells. -
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BDM91514
0 ImagesCat. No.: HY-155047CAS No.: 2892824-90-5BDM91514 improves antibiotic potency through AcrB inhibition. BDM91514 prevents the growth of E. coliBW25113 (EC90: 8 μM) in the presence of 8 μg/mL Pyridomycin. BDM91514 has suitable plasma and microsomal stability. -
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Eumenitin
0 ImagesCat. No.: HY-P11163CAS No.: 255720-68-4Eumenitin is an antibacterial peptide with strong membrane activity, broad-spectrum antibacterial activity, and almost no hemolytic toxicity. Eumenitin has inhibitory effects on various Gram positive and Gram negative bacteria. Eumenitin can induce the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin can be used in the research of infectious conditions. -
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Enrofloxacin-d5 hydriodide
0 ImagesCat. No.: HY-B0502AS1CAS No.: 1219795-24-0Synonyms: BAY Vp 2674-d5 hydriodide; PD160788-d5 hydriodideEnrofloxacin-d5 (hydriodide) is the deuterium labeled Enrofloxacin (monohydrochloride). Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. -
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Erdosteine-13C4
0 ImagesCat. No.: HY-B0289SCAS No.: 2748548-92-5Synonyms: RV 144-13C4Erdosteine-13C4 is a 13C-labeled Erdosteine. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects. -
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Antimicrobial agent-3
0 ImagesCat. No.: HY-147876CAS No.: 1902712-34-8 -
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Fenvalerate-d5
0 ImagesCat. No.: HY-B2006SCAS No.: 1246815-00-8Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide. -
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PD 124816
0 ImagesCat. No.: HY-W780694CAS No.: 112654-98-5PD 124816 is an orally active fluoroquinolone antibiotic. PD 124816 exerts broad-spectrum antibacterial effects by inhibiting DNA gyrase (topoisomerase IV), and it has no cross-resistance with commonly used antibiotics. PD 124816 is effective against both Gram-positive and Gram-negative bacteria (MIC₉₀ ≤ 0.06 μg/mL), and the MIC₉₀ for anaerobic bacteria (Peptostreptococcus fragi) is 1 μg/mL. PD 124816 exhibits complete bactericidal activity in a mouse model of Mycobacterium leprae infection. PD 124816 can be used for studying mixed infections and infections caused by drug-resistant bacteria. -
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Isovalerylspiramycin II
0 ImagesCat. No.: HY-N15251CAS No.: 848080-53-5Isovalerylspiramycin II is one of the core active components of the multi-component antibiotic Bitespiramycin. Isovalerylspiramycin II shows antibacterial activity and can be used for research of bacterial infection. -
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Utidelone (Standard)
0 ImagesCat. No.: HY-15278RCAS No.: 189453-10-9Synonyms: Epothilone D (Standard); UTD1 (Standard); KOS 862 (Standard)Utidelone (Standard) (Epothilone D (Standard)) is the analytical standard ofUtidelone. This product is intended for research and analytical applications. Utidelone is a potent microtubule stabilizer. -
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Toxoflavin-13C4
0 ImagesCat. No.: HY-100760SCAS No.: 2300178-70-3Synonyms: Xanthothricin-13C4; Toxoflavine-13C4; PKF-118-310-13C4Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity. Antibiotic properties. -
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Oncocin
0 ImagesCat. No.: HY-P11080CAS No.: 1235497-90-1Oncocin is an antibacterial peptide. It belongs to proline-rich antimicrobial peptides (PrAMPs). Oncocin works against Gram-negative bacteria. It has MIC values of 0.125-8 μg/mL for 34 strains and clinical isolates of Enterobacteriaceae and nonfermenters. Oncocin binds to the substrate-binding domain of the chaperone DnaK. The binding has dissociation constants in the micromolar range. This binding causes protein misfolding and aggregation and the bacteria death. -
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