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CCR Related Products (135)
Related Products (135)
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Vicriviroc
0 ImagesCat. No.: HY-B0155CAS No.: 306296-47-9Synonyms: SCH 417690; SCH-D; MK-7690 free baseVicriviroc (SCH 417690) is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer.
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Anti-CCL28 Antibody
0 ImagesCat. No.: HY-P992198
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Velaprumig
0 ImagesCat. No.: HY-P991168CAS No.: 2988741-17-7Velaprumig is a monoclonal antibody targeting human CD99, CCL25, and anti-human Aβ (Aβ-47F). Velaprumig regulates immune cell migration and reduces β-amyloid-related pathological processes, exerting immunomodulatory and potential anti - Alzheimer's disease activities.
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ALK4290 dihydrochloride
0 ImagesCat. No.: HY-136788ACAS No.: 1372127-19-9Synonyms: AKST4290 dihydrochloride; BI144807 dihydrochlorideALK4290 dihydrochloride (AKST4290 dihydrochlorid) is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism.
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PF-232798
0 ImagesCat. No.: HY-14388CAS No.: 849753-15-7
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Anti-inflammatory agent 87
0 ImagesCat. No.: HY-119050CAS No.: 749860-43-3Anti-inflammatory agent 87 (compound 72) is a potential anti-inflammatory agent, whose precursor is an inhibitor targeting the binding of thymus and activation-regulated chemokine (TARC/CCL17) to Hut78 cells. Anti-inflammatory agent 87 can be used in the research of allergic diseases, autoimmune diseases, transplant rejection and other conditions.
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ZK 756326
0 ImagesCat. No.: HY-101038CAS No.: 874911-96-3
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(Rac)-PF-4136309
0 ImagesCat. No.: HY-13245BCAS No.: 857679-55-1Synonyms: (Rac)-INCB8761(Rac)-PF-4136309 is an isoform of PF-4136309 (HY-13245), which is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
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(s)-PF-4136309
0 ImagesSynonyms: (s)-INCB8761(s)-PF-4136309 is the isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
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HGS101
0 ImagesCat. No.: HY-P991541HGS101 is a fully human CCR5 monoclonal antibody with high affinity to CCR5. HGS101 binds to the 2nd extracellular loop (ECL-2) and acts as a signal antagonist. HGS101 restores Maraviroc (HY-13004) inhibition of Maraviroc-resistant HIV-1 infection of PBMCs. HGS101 shows anti-HIV activity by inhibiting CCR5 signaling in simian immunodeficiency virus-uninfected RMs models.
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Vicriviroc malate
0 ImagesCat. No.: HY-B0155BCAS No.: 541503-81-5Synonyms: SCH 417690 malate; SCH-D malate; MK-7690Vicriviroc (SCH 417690) malate is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc malate can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer.
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Murabutide
0 ImagesCat. No.: HY-106055CAS No.: 74817-61-1Murabutide is an immunomodulator and also a NOD2 receptor agonist. Murabutide enhances the signal transduction of ATR and NOD2, mediates the activation of the DDR pathway, and thereby repairs radiation-induced DNA double-strand breaks. Murabutide inhibits radiation-induced cell apoptosis and protects cells and mice from radiation-induced toxic damage. Murabutide induces the expression and DNA-binding activity of Oct-1 in macrophages, thereby inhibiting the transcription and replication of HIV-1. Murabutide reduces the expression levels of CD4 and CCR5 on the surface of macrophages, and induces the secretion of β-chemokines, TNF-α and IL-6. Murabutide enhances non-specific viral resistance and targets reticuloendothelial cells. Murabutide can be used in research related to radiation-induced damage and human immunodeficiency virus type 1 infection.
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CCL17-IN-1
0 ImagesCat. No.: HY-185144CAS No.: 3104330-39-1CCL17-IN-1 (Compound Ex.132) is a CCL17 secretion inhibitor with an EC50 of 0.2 nM. CCL17-IN-1 can be used in the research of autoimmune diseases, dermatological conditions, and respiratory disorders.
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Anti-Mouse CCR5 Antibody (C5Mab-2)
0 ImagesCat. No.: HY-P991788Anti-Mouse CCR5 Antibody (C5Mab-2) reacts with mouse CCR5. CCR5 is a seven-pass transmembrane protein from the GPCR family. Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682).
