Acyltransferase Inhibitor
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A 922500 (Standard)
0 ImagesSynonyms: DGAT-1 Inhibitor 4a (Standard)A 922500 (Standard) is the analytical standard of A 922500 (HY-10038). This product is intended for research and analytical applications. A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of 9 and 22 nM against human and mouse DGAT-1, respectively.
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Roselipin 1B
0 ImagesCat. No.: HY-N14584CAS No.: 232258-18-3Roselipin 1B inhibits diacylglycerol acyltransferases (DGAT) of rat hepatic microcosm.
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Triethylcholine iodide
0 ImagesCat. No.: HY-W127668CAS No.: 5957-17-5Triethylcholine iodide is a choline acetyltransferase inhibitor and a regulator of the acetylcholine synthesis pathway. Triethylcholine iodide inhibits acetylcholine synthesis in brain tissues and blocks neuromuscular and autonomic ganglionic transmission. Triethylcholine iodide exerts weak curare-like effects at extremely high concentrations. Triethylcholine iodide elevates the pentylenetetrazol seizure threshold, alters electroencephalogram patterns in Felis catus, but does not affect the maximal electroshock seizure threshold in Oryctolagus cuniculus. Triethylcholine iodide can be used in seizure-related research.
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Glisoprenin B
0 ImagesCat. No.: HY-N14573CAS No.: 144376-63-6Glisoprenin B is a cholesterol acyltransferase (ACAT) inhibitor.
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Idalaptican pegol
0 ImagesCat. No.: HY-185926CAS No.: 2364414-05-9Synonyms: NOX-D21; AON-D21Ldalaptican pegol (AON-D21; NOX-D21) is a PEGylated mixed RNA/DNA L-aptamer that specifically binds to complement C5a. Ldalaptican pegol binds to C5a and the C5a moiety on uncleaved C5, thereby blocking C5a signaling. This inhibition suppresses downstream inflammatory responses, immune cell infiltration and chemotaxis, the release of pro-fibrotic factors, and abnormalities in lipid metabolism signaling pathways. Ldalaptican pegol can also alleviate allograft rejection. Ldalaptican pegol can be used in research on inflammatory muscle diseases, Duchenne muscular dystrophy (DMD), diabetes, renal fibrosis, and allograft organ transplant rejection.
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CMX410
0 ImagesCMX410 is an orally active and selective Mycobacterium tuberculosis Pks13 acyltransferase domain inhibitor and anti-bacterial agent. CMX410 reacts with the catalytic serine of the Pks13-AT domain to form a stable β-lactam ring, disables the enzyme’s active site, reduces trehalose monomycolate and trehalose dimycolate levels, triggers cell lysis, and reduces intracellular bacterial burden. CMX410 can be used for the research of tuberculosis.
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Roselipin 2A
0 ImagesCat. No.: HY-N14580CAS No.: 232258-26-3Roselipin 2A inhibits diacylglycerol acyltransferases (DGAT) of rat hepatic microcosm.
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Amidepsin B
0 ImagesCat. No.: HY-N14793CAS No.: 169181-29-7Amidepsin B is a diacylglycerol acyltransferase (DGAT) inhibitor.
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Amidepsin C
0 ImagesCat. No.: HY-N14794CAS No.: 169181-30-0Amidepsin C is a diacylglycerol acyltransferase (DGAT) inhibitor.
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Phenylpyropene B
0 ImagesCat. No.: HY-N14688CAS No.: 556013-83-3Phenylpyropene B can inhibit ACAT activity with IC50 of 12.8 μM.
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ACAT-IN-1 cis isomer
0 ImagesCat. No.: HY-101648CAS No.: 145961-79-1ACAT-IN-1 cis isomer is a potent ACAT inhibitor with an IC50 of 100 nM.
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FCE 28654
0 ImagesCat. No.: HY-U00369CAS No.: 169474-77-5FCE 28654 is an inhibitor of acylCoA: cholesterol acyltransferase (ACAT), weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver, with IC50s of 2.55, 1.08 and 5.69 μM, respcetively.
