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DYRK Related Products (44)
Related Products (44)
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DYRK2-IN-1
0 ImagesCat. No.: HY-161014CAS No.: 3036481-22-5DYRK2-IN-1 (Compd 54) is an orally bioavailable DYRK2 inhibitor, with an IC50 of 14 nM. DYRK2-IN-1 (Compd 54) can be used in the study of prostate cancer.
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Aristolactam A IIIa
0 ImagesCat. No.: HY-N2892CAS No.: 97399-91-2Synonyms: Aristololactam A IIIa; Sch 546909Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells.
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DYRKs-IN-2
0 ImagesCat. No.: HY-128759CAS No.: 1386980-04-6
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Dyrk1A-IN-10
0 ImagesCat. No.: HY-159496CAS No.: 2891824-14-7
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FINDY
0 ImagesCat. No.: HY-152183CAS No.: 1507367-37-4FINDY is a folding intermediate-selective inhibitor of DYRK1A. FINDY can inhibit Ser97 autophosphorylation with an IC50 value of 35 μM. FINDY can be used for the research of neurological disorder. FINDY is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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tBID (Standard)
0 ImagesCat. No.: HY-100464RCAS No.: 1639895-85-4
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LDN-209929 dihydrochloride (Standard)
0 ImagesCat. No.: HY-110320RCAS No.: 1784281-97-5LDN-209929 dihydrochloride (Standard) is the analytical standard of LDN-209929 (dihydrochloride) (HY-110320). This product is intended for research and analytical applications. LDN-209929 dihydrochloride is a potent and selective haspin Kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 (HY-13455).
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INDY (Standard)
0 ImagesCat. No.: HY-108476RCAS No.: 1169755-45-6INDY (Standard) is the analytical standard of INDY (HY-108476). This product is intended for research and analytical applications. INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells.
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GSK-626616 (Standard)
0 ImagesCat. No.: HY-105309RCAS No.: 1025821-33-3GSK-626616 (Standard) is the analytical standard of GSK-626616 (HY-105309). This product is intended for research and analytical applications. GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia.
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Aristolactam BIII
0 ImagesCat. No.: HY-122989CAS No.: 53948-10-0
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Harmine hydrochloride (Standard)
0 ImagesHarmine Hydrochloride (Telepathine Hydrochloride) is a natural DYRK inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.
