2. Signaling Pathways
  3. GPCR/G Protein
  4. G protein-coupled Bile Acid Receptor 1
  5. G protein-coupled Bile Acid Receptor 1 Inhibitor

G protein-coupled Bile Acid Receptor 1 Inhibitor

G protein-coupled Bile Acid Receptor 1 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-180268
    TGR5 agonist 8
    		Inhibitor
    TGR5 agonist 8 (Compound 7i) is a TGR5 agonist with an EC₅₀ of 571 nM. TGR5 agonist 8 significantly reduced blood glucose and food intake in acute diabetic mice and long-term inhibited the mice's appetite. TGR5 agonist 8 can be used for research on diabetes and obesity.
  • HY-B0575
    Triamterene
    		Inhibitor 99.90%
    Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic. Triamterene is an inhibitor of the TGR5 receptor.
  • HY-B0575R
    Triamterene (Standard)
    		Inhibitor
    Triamterene (Standard) is the analytical standard of Triamterene. This product is intended for research and analytical applications. Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic. Triamterene as an inhibitor of the TGR5 receptor.