Lipase
Lipase is a water-soluble enzyme that can catalyze the ester bond hydrolysis of lipids, decompose and metabolize fat molecules. Lipase is produced primarily by the pancreas and helps the body digest fats and oils. Lipase inhibitors are able to reduce the digestion and absorption of fat, thereby reducing collective caloric intake and weight loss. Lipase inhibitors are commonly used to suppress diseases such as obesity, hyperlipidemia, and pancreatitis.
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Lipase Related Products (129)
Related Products (129)
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Antibodies (6)
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Pungenin
0 ImagesCat. No.: HY-W719455CAS No.: 55483-00-6Pungenin is a compound that can be isolated from Leontopodium leontopodioides. Pungenin exhibits lipase inhibitory activity. Pungenin reuduces triglyceride absorption.
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Dehydrodicatechin A
0 ImagesCat. No.: HY-N21753CAS No.: 36048-23-4Dehydrodicatechin A is a biflavan catechin dimer and antioxidant. Dehydrodicatechin A is isolated from the roots of Hagenia abyssinica, the stem bark of Choerospondias axillaries, the stems of Entada phaseoloides, and Calligonum comosum. Dehydrodicatechin A exhibits ABTS+ radical cation, DPPH, ABTS, and superoxide anion radical scavenging activities, as well as ferric reducing/antioxidant power. Dehydrodicatechin A inhibits Lipase. Dehydrodicatechin A is used in studies on polycystic ovary syndrome, Ehrlich ascites, and Doxorubicin (HY-15142)-induced cardiotoxicity.
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Hexane-1,6-diol-d4
0 ImagesCat. No.: HY-W010505SCAS No.: 6843-76-1Hexane-1,6-diol-d4 is the deuterium labeled Hexane-1,6-diol (HY-W010505). Hexane-1,6-diol is a 6-carbon straight-chain diol with hydroxyl groups at both ends. Hexane-1,6-diol can be used as an additive for drilling fluids. Hexane-1,6-diol can also be used as a substrate in life science-related research.
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Ciwujianoside D2
0 ImagesCat. No.: HY-N12294CAS No.: 114892-57-8Ciwujianoside D2, a saponin compound, can enhance pancreatic lipase activity in vitro.
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SOL-116
0 ImagesCat. No.: HY-P991937
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LAS195319
0 ImagesCat. No.: HY-123862CAS No.: 1605328-04-8LAS195319 is an orally active and potent inhibitor against PI3Kδ with an IC50 value of 0.5 nM. LAS195319 is also a highly selective inhibitor against an extensive panel of proteins, lipid kinases and GPCRs. LAS195319 causes an inhibition of neutrophil and eosinophil infiltration. LAS195319 is promising for research of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
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Lipid OA2 dihydrochloride
0 ImagesCat. No.: HY-172535Lipid OA2 dihydrochloride is an ionizable cationic lipid that can be used to prepare single-component lipid nanoparticles for siRNA delivery. Lipid OA2 dihydrochloride can effectively deliver SOCS1-siRNA to dendritic cells, silence the SOCS1 gene, and enhance their antigen-presenting ability and pro-inflammatory factor secretion capacity.
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5-Hydroxyaloin A
0 ImagesCat. No.: HY-N11721CAS No.: 138373-23-65-Hydroxyaloin A is a polyphenolic antioxidant agent. 5-Hydroxyaloin A forms hydrogen bonding interactions at lipase’s active site and SOD’s active site with low binding energy. 5-Hydroxyaloin A inhibits microsomal lipid peroxidation induced by ferrous-cysteine, reducing malondialdehyde production. 5-Hydroxyaloin A can be used for the research of obesity.
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α-Glucosidase-IN-123
0 ImagesCat. No.: HY-187714α-Glucosidase-IN-123, a hybrid derivative of baicalein and cinnamic acid, acts as an inhibitor of α-glucosidase. α-Glucosidase-IN-123 enhances glucose uptake in insulin-resistant hepatocytes without significant cytotoxicity. α-Glucosidase-IN-123 exhibits lipase inhibitory activity and DPPH free radical scavenging activity, and it can be used in the research of type 2 diabetes.
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Ciwujianoside C4
0 ImagesCat. No.: HY-N12296CAS No.: 114906-75-1Ciwujianoside C4, a saponin compound, can enhance pancreatic lipase activity in vitro.
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(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate
0 ImagesCat. No.: HY-N8989CAS No.: 201012-14-8
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(3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate
0 ImagesCat. No.: HY-N18267CAS No.: 1820891-39-1(3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate is a polyacetylene found in Atractylodes lancea rhizome. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate inhibits human pancreatic lipase inhibitor with an IC50 of 39.91 μM. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate can be used for the research of obesity.
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Morusalnol A
0 ImagesCat. No.: HY-N17567CAS No.: 1941207-42-6
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Ebelactone A
0 ImagesEbelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis.
