2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Cytoskeleton
  4. PAK
  5. PAK1 Isoform
  6. PAK1 Activator

PAK1 Activator

PAK1 Activators (2):

Cat. No. Product Name Effect Purity
  • HY-12005
    Fingolimod hydrochloride
    		Activator 99.95%
    Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1-phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator.
  • HY-11063
    Fingolimod
    		Activator 99.56%
    Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.