2. Signaling Pathways
  3. Epigenetics
    TGF-beta/Smad
  4. PKC
  5. PKCζ Isoform
  6. PKCζ Inhibitor

PKCζ Inhibitor

PKCζ Inhibitors (9):

Cat. No. Product Name Effect Purity
  • HY-10230
    Midostaurin
    		Inhibitor 99.95%
    Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor.
  • HY-13689
    Go 6983
    		Inhibitor 98.42%
    Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.
  • HY-18980
    Rottlerin
    		Inhibitor 98.15%
    Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM.
  • HY-123979
    ζ-Stat
    		Inhibitor
    ζ-Stat (NSC37044) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM.
  • HY-18713
    CRT0066854
    		Inhibitor 99.59%
    CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor.
  • HY-117366
    PS432
    		Inhibitor
    PS432 is a PKC inhibitor with IC50s of 16.9 μM (PKCι) and 18.5 μM (PKCζ), respectively.
  • HY-123979A
    ζ-Stat trisodium
    		Inhibitor
    ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM.
  • HY-18713A
    CRT0066854 hydrochloride
    		Inhibitor
    CRT0066854 hydrochloride is a potent and selective atypical PKCs inhibitor.
  • HY-124308
    PS315
    		Inhibitor
    PS315, a derivative of PS48 (HY-15967), is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing a displacement of the active site residue Lys111.