Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2533)
Related Products (2533)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Cycloaspeptide A
0 ImagesCat. No.: HY-125298CAS No.: 109171-13-3Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity.
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MMV665917
0 ImagesCat. No.: HY-165555CAS No.: 904576-65-4MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease.
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AcrB-IN-2
0 ImagesCat. No.: HY-149810CAS No.: 2890177-90-7AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
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PIQ-2
0 ImagesCat. No.: HY-169289CAS No.: 3035141-23-9PIQ-2 (compound 54) is a antiprotozoal agent with the IC50 values of 9.4 nM and 1.6 nM against IP. falciparum 3D7I and B. divergens Rouen,respectively.
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Noracronycine
0 ImagesCat. No.: HY-N8465CAS No.: 13161-79-0Synonyms: NSC 103005Noracronycine is an alkaloid originally isolated from G. pentaphylla that has antimalarial activity. It is active against P. yoelii when used at a concentration of 10 μg/mL.
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Dimethomorph-d8
0 ImagesCat. No.: HY-B0846SCAS No.: 1346606-71-0Dimethomorph-d8 is the deuterium labeled Dimethomorph. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM.
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Insecticidal agent 10
0 ImagesCat. No.: HY-163560CAS No.: 3026314-21-3Insecticidal agent 10 (Compound 8c) is an inhibitor for chitinase, which inhibits OfChi-h and OfChtI with IC50 of 1.51 and 9.21 nM, respectively. Insecticidal agent 10 inhibits growth of Ostrinia furnacalis with LC50 of 22.14 mg/L.
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Chloroquine-d5 diphosphate
0 ImagesCat. No.: HY-17589SCAS No.: 1854126-42-3Chloroquine-d5 (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
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α-Artemether-d3
0 ImagesCat. No.: HY-W703432CAS No.: 93861-34-8Synonyms: Methoxy-d3α-Artemether-d3 (Methoxy-d3) is the deuterium labeled α-Artemether (HY-137217). α-Artemether is an antimalarial compound.
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Brevicompanine B
0 ImagesCat. No.: HY-N8513CAS No.: 215121-47-4Brevicompanine B, a diketopiperazine alkaloid, is an antiplasmodial agent. Brevicompanine B is active against the malaria parasite Plasmodium falciparum 3D7 IC50 of 35 mg/mL.
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RyRs activator 4
0 ImagesCat. No.: HY-155334CAS No.: 2987900-56-9RyRs activator 4 (compound B18) is an insect ryanodine receptor activator. RyRs activator 4 has alarvicidal activity of Mythimna separata with an LC50 value of 1.32 mg/L.
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PfSUB1-IN-1
0 ImagesCat. No.: HY-159479PfSUB1-IN-1 (compound 4c) is a plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1) Inhibitor (IC50: 15 nM). PfSUB1 is an antimalarial target. PfSUB1-IN-1 inhibits the growth of a genetically modified P. falciparum line expressing reduced levels of PfSUB1 13-fold more efficiently compared to a wild-type parasite line.
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MMV666810
0 ImagesCat. No.: HY-141836CAS No.: 1450666-97-3MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM).
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Benfuracarb (Standard)
0 ImagesCat. No.: HY-B2041RCAS No.: 82560-54-1Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
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FM-1088
0 ImagesCat. No.: HY-162778CAS No.: 2410561-64-5FM-1088 is an insecticide. FM-1088 can be used in research related to crop disease and insect pest control.
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Cycloguanil hydrochloride (Standard)
0 ImagesSynonyms: Chlorguanide triazine hydrochloride (Standard)Cycloguanil hydrochloride (Standard) is the analytical standard of Cycloguanil hydrochloride (HY-12784A). This product is intended for research and analytical applications. Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil hydrochloride blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil hydrochloride inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil hydrochloride also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity.
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Antileishmanial agent-13
0 ImagesCat. No.: HY-151935CAS No.: 853725-86-7Antileishmanial agent-13 is a quinoline-isatin hybrid, acts as an antileishmanial agent against L. Major Leishmania strain. Antileishmanial agent-13 acquires the antileishmanial activity via the anti-folate mechanism. Antileishmanial agent-13 has potent inhibition against both promastigote and amastigote forms with IC50s of 0.604 μM and 0.508 μM, respectively.
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Salviandulin E
0 ImagesCat. No.: HY-N11550CAS No.: 158994-32-2Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL.
