1. Anti-infection
  2. Parasite
  3. MMV666810

MMV666810 

Cat. No.: HY-141836
Handling Instructions

MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM).

For research use only. We do not sell to patients.

MMV666810 Chemical Structure

MMV666810 Chemical Structure

CAS No. : 1450666-97-3

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Description

MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM).

Molecular Weight

442.43

Formula

C₂₃H₂₁F₃N₄O₂

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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MMV666810
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HY-141836
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