Ras Modulator
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Palmostatin M
0 ImagesCat. No.: HY-152951CAS No.: 1351669-68-5Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC50 of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research.
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KRAS G12D modulator-1
0 ImagesCat. No.: HY-153555CAS No.: 2883034-05-5KRAS G12D modulator-1 (compound 6) is a potent KRAS G12D modulator with IC50 values of 1-10 μM for NEA-G12D, PPI-G12D, and p ERK-AGS, respectively. KRAS G12D modulator-1 can be used in research of cancer.
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Neoantimycin
0 ImagesCat. No.: HY-121459CAS No.: 22862-63-1Neoantimycin is a GRP78/BiP and K-Ras regulator with anticancer activity. Its biosynthesis is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system.
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(+)-Oxanthromicin
0 ImagesCat. No.: HY-120885CAS No.: 1616622-08-2(+)-Oxanthromicin (Compound 1) mislocalizes the oncogenic mutant K-Ras from the plasma membrane of intact Madin-Darby canine kidney (MDCK) cells, and exhibits thereby antitumor efficacy.
