Palmostatin M
Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC50 of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 1351669-68-5
- Formula: C22H43NO4S
- Molecular Weight:417.65
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Palmostatin M potently inhibits recombinant human APT1 in a biochemical assay with an IC50 of 2.5 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1351669-68-5
-
Molecular Weight 417.65
-
Formula C22H43NO4S
-
SMILES
C(CCCS(CCCN(C)C)(=O)=O)[C@H]1[C@H](CCCCCCCCCC)C(=O)O1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)