Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
-
Reference Standards Verwandte Produkte (11772)
Verwandte Produkte (11772)
-
Necrosulfonamide (Standard)
0 ImagesArt. -Nr.: HY-100573RCAS. Nr.: 1360614-48-7Necrosulfonamide (Standard) is the analytical standard of Necrosulfonamide (HY-100573). This product is intended for research and analytical applications. Necrosulfonamide is a MLKL and Gasdermin D (GSDMD) inhibitor, capable of separately inhibiting necroptosis and pyroptosis of cells. Necrosulfonamide does not affect the activation of upstream signals, but specifically inhibits the downstream executor oligomerization step. Necrosulfonamide reduces the expression of the key kinases NLRP3 and caspase-1 involved in necroptosis and pyroptosis, activate the Nrf2 pathway and the downstream antioxidant enzymes, and also downregulates a variety of inflammatory factors. Necrosulfonamide plays significant roles in various diseases such as neurodegenerative diseases (such as Parkinson’s disease), tissue damage and ischemia-reperfusion injury, inflammatory bowel disease, osteoarthritis and fracture repair, and hair loss by regulating two important programmed necrosis pathways.
-
DSP-4 hydrochloride (Standard)
0 ImagesArt. -Nr.: HY-103210RCAS. Nr.: 40616-75-9Synonyms: Neurotoxin DSP 4 hydrochloride (Standard)DSP-4 hydrochloride (Standard) is the analytical standard of DSP-4 hydrochloride (HY-103210). This product is intended for research and analytical applications. DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons.
-
Picrotoxinin (Standard)
0 ImagesArt. -Nr.: HY-B1494RCAS. Nr.: 17617-45-7Picrotoxinin (Standard) is the analytical standard of Picrotoxinin. This product is intended for research and analytical applications. Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC50 of 1.15 μM.
-
Balofloxacin (Standard)
0 ImagesArt. -Nr.: HY-B0159RCAS. Nr.: 127294-70-6Synonyms: Q-35 (Standard)Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections.
-
Velagliflozin proline hydrate (Standard)
0 ImagesArt. -Nr.: HY-109018BRCAS. Nr.: 1661838-94-3Velagliflozin proline hydrate (Standard) is the analytical standard of Velagliflozin (proline hydrate) (HY-109018B). This product is intended for research and analytical applications. Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations.
-
Rubiadin (Standard)
0 ImagesRubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections.
-
Sacubitrilat impurity 34 (Standard)
0 ImagesArt. -Nr.: HY-78834RCAS. Nr.: 149709-58-0[(1R)-2-(Biphenyl-4-yl)-1-formylethyl]carbamic acid tert-butyl ester (Standard) is the analytical standard of [(1R)-2-(Biphenyl-4-yl)-1-formylethyl]carbamic acid tert-butyl ester. This product is intended for research and analytical applications.
-
3-Chloropropiophenone (Standard)
0 ImagesArt. -Nr.: HY-107857RCAS. Nr.: 936-59-4Synonyms: β-Chloroethyl phenyl ketone (Standard)3-Chloropropiophenone (Standard) is the analytical standard of 3-Chloropropiophenone (HY-107857). This product is intended for research and analytical applications. 3-Chloropropiophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
-
Valifenalate (Standard)
0 ImagesSynonyms: IR5885 (Standard); Valiphenal (Standard)Valifenalate (Standard) is the analytical standard of Valifenalate. This product is intended for research and analytical applications. Valifenalate (IR5885; Valiphenal) is an insecticide agent and fungicide, which is approved for application on high-value crops such as grapes, tomatoes and other vegetables. Valifenalate interferes with cell-wall synthesisValifenalate is effective against various types of mildew. Valifenalate can be used against crown rot of rose cuased by Phytophthora citrophthora. Valifenalate induces non-adverse thyroid changes via adaptive induction of uridine 5’-diphosphoglucuronosyltransferase (UGT) in the liver of dogs and rats.
-
BIRT 377 (Standard)
0 ImagesArt. -Nr.: HY-110117RCAS. Nr.: 213211-10-0BIRT 377 (Standard) is the analytical standard of BIRT 377 (HY-110117). This product is intended for research and analytical applications. BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1). BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders.
-
Bicyclopyrone (Standard)
0 ImagesArt. -Nr.: HY-135767RCAS. Nr.: 352010-68-5Bicyclopyrone (Standard) is the analytical standard of Bicyclopyrone. This product is intended for research and analytical applications. Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd).
-
Methylsticin (Standard)
0 ImagesMethylsticin (Standard) is the analytical standard of Methylsticin. This product is intended for research and analytical applications. Methylsticin is a kavalactone isolated from the Piper methysticum . Methylsticin exhibit osteoclast formation inhibitory activity.
-
Methyl 4-ethoxy-3-oxobutanoate (Standard)
0 ImagesArt. -Nr.: HY-Z0785RCAS. Nr.: 415678-65-8Methyl 4-ethoxy-3-oxobutanoate (Standard) is the analytical standard of Methyl 4-ethoxy-3-oxobutanoate. This product is intended for research and analytical applications.
-
Mardepodect hydrochloride (Standard)
0 ImagesArt. -Nr.: HY-50098ARCAS. Nr.: 2070014-78-5Synonyms: PF-2545920 hydrochloride (Standard)Mardepodect (hydrochloride) (Standard) is the analytical standard of Mardepodect (hydrochloride). This product is intended for research and analytical applications. Mardepodect hydrochloride (PF-2545920 hydrochloride) is a potent, orally active and selective PDE10A inhibitor with an IC50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect hydrochloride can cross the blood-brain barrier.
-
Irdabisant (Standard)
0 ImagesArt. -Nr.: HY-109968RCAS. Nr.: 1005402-19-6Synonyms: CEP-26401 (Standard)Irdabisant (Standard) is the analytical standard of Irdabisant (HY-109968). This product is intended for research and analytical applications. Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC50 of 13.8 μM. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment.
-
DMNB (Standard)
0 ImagesArt. -Nr.: HY-100705RCAS. Nr.: 20357-25-9Synonyms: 6-Nitroveratraldehyde (Standard)DMNB (Standard) is the analytical standard of DMNB (HY-100705). This product is intended for research and analytical applications. DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems.
-
Niraparib (R-enantiomer) (Standard)
0 ImagesArt. -Nr.: HY-10619DRCAS. Nr.: 1038915-58-0Synonyms: MK 4827 (R-enantiomer) (Standard)Niraparib (R-enantiomer) (Standard) is the analytical standard of Niraparib (R-enantiomer) (HY-10619D). This product is intended for research and analytical applications. Niraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM.
-
Isoflupredone acetate (Standard)
0 ImagesIsoflupredone acetate (Standard) is the analytical standard of Isoflupredone acetate. This product is intended for research and analytical applications. Isoflupredone acetate is a corticosteroids with anti-inflammatory activity. Isoflupredone acetate can be used for research ketosis, musculoskeletal disorders, hypersensitivity, infections, inflammatory diseases in cows, horse, pigs, et al..
-
Rebamipide impurity 5 (Standard)
0 ImagesArt. -Nr.: HY-Z4548RCAS. Nr.: 23976-54-76-Bromo-4-(bromomethyl)quinolin-2(1H)-one (Impurity) (Standard) is the analytical standard of 6-Bromo-4-(bromomethyl)quinolin-2(1H)-one (Impurity). This product is intended for research and analytical applications.
-
4,4'-Disulfanediylbis(2-aminobutanoic acid) (Standard)
0 Images4,4'-Disulfanediylbis(2-aminobutanoic acid) (Standard) is the analytical standard of 4,4'-Disulfanediylbis(2-aminobutanoic acid) (HY-W009390A). This product is intended for research and analytical applications. 4,4'-Disulfanediylbis(2-aminobutanoic acid) is an endogenous metabolite.
