40616-75-9
40616-75-9
Chemical Structure
DSP-4 hydrochloride
Synonym(s): Neurotoxin DSP 4 hydrochloride
- CAS No.: 40616-75-9
- Formula:C11H16BrCl2N
- Molecular Weight:313.06
IUPAC Name: N-(2-bromobenzyl)-2-chloro-N-ethylethan-1-amine hydrochloride
InChIKey: NDDRNRRNYOULND-UHFFFAOYSA-N
SMILES: CCN(CCCl)CC1=CC=CC=C1Br.[H]Cl
Biological Activity: DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons[1][2].
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DSP-4 hydrochloride | 98.0% | DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons. | ||||||||||||||||||||
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DSP-4 hydrochloride (Standard) | ≥98% | DSP-4 hydrochloride (Standard) is the analytical standard of DSP-4 hydrochloride (HY-103210). This product is intended for research and analytical applications. DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.97
HY-121602DSP 4 free base -
Similarity Score 0.82
HY-139192ABrophenexin free base -
Similarity Score 0.79
HY-W611371FP802 -
Similarity Score 0.73
HY-W7212592-Bromoamphetamine hydrochloride -
Similarity Score 0.72
HY-W098607N1-Benzyl-N1-methylethane-1,2-diamine -
Similarity Score 0.72
HY-W042417R2-(Benzyl(methyl)amino)ethanol (Standard) -
Similarity Score 0.71
![3-[Benzyl(methyl)amino]propanoic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w151576.gif)
HY-W1515763-[Benzyl(methyl)amino]propanoic acid -
Similarity Score 0.70
HY-183840PP185 -
Similarity Score 0.70
HY-45215Benzeneethanamine,2-bromo-a,a-dimethyl -
Explore the MedChemAI to find more analogs
![3-[Benzyl(methyl)amino]propanoic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w151576.gif)
References
- [1]. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41. [Content Brief]
- [2]. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23. [Content Brief]
