1. Membrane Transporter/Ion Channel
  2. SGLT

Velagliflozin 

Cat. No.: HY-109018
Handling Instructions

Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

For research use only. We do not sell to patients.

Velagliflozin Chemical Structure

Velagliflozin Chemical Structure

CAS No. : 946525-65-1

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

IC50 & Target

SGLT2[1]

In Vitro

Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity[1].

In Vivo

Velagliflozin (1 mg/kg, p.o.) increases cholesterol, albumin, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), and urinary glucose excretion, and decreases respiratory exchange ratio in cats[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5288 mL 12.6438 mL 25.2876 mL
5 mM 0.5058 mL 2.5288 mL 5.0575 mL
10 mM 0.2529 mL 1.2644 mL 2.5288 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

395.45

Formula

C₂₃H₂₅NO₅

CAS No.

946525-65-1

SMILES

O[[email protected]]1[[email protected]](C2=CC(CC3=CC=C(C4CC4)C=C3)=C(C#N)C=C2)O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]1O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Velagliflozin
Cat. No.:
HY-109018
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Velagliflozin

Cat. No.: HY-109018