2. Signaling Pathways
  3. Immunology/Inflammation
  4. SphK
  5. SphK Activator

SphK Activator

SphK Activators (3):

Cat. No. Product Name Effect Purity
  • HY-18739
    Phorbol 12-myristate 13-acetate
    		Activator 99.66%
    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator. Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells.
  • HY-101572
    MHP
    		Activator 98.23%
    MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity.
  • HY-124042
    K6PC-5
    		Activator 99.85%
    K6PC-5, a ceramide derivative, is a sphingosine kinase 1(SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels. K6PC-5 has the potential for skin diseases involving abnormal keratinocyte, and neurodegeneration and virus infection research.