Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11092)
Related Products (11092)
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Heptylbenzene-d20
0 ImagesCat. No.: HY-W088426S2CAS No.: 634897-84-0Synonyms: 1-Phenylheptane, (n-Heptylbenzene)-d20Heptylbenzene-d20 is the deuterium labeled Heptylbenzene.
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Geranylgeraniol-d5
0 ImagesCat. No.: HY-W011474SCAS No.: 174873-05-3Geranylgeraniol-d5 is the deuterium labeled Geranylgeraniol (HY-W011474). Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model.
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Piperazin-2-one-d6
0 ImagesPiperazin-2-one-d6 is the deuterium labeled Piperazin-2-one (HY-20128). Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds.
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Envudeucitinibum hydrochloride
0 ImagesCat. No.: HY-153701S1CAS No.: 3009133-87-0Synonyms: Envudeucitinib hydrochloride; ESK-001 hydrochlorideEnvudeucitinibum (Envudeucitinib; ESK-001) hydrochloride is an orally active and selective TYK2 allosteric inhibitor with an IC50 range of 104-149 nM. Envudeucitinibum hydrochloride blocks JH1 catalytic activity by specifically binding to the JH2 domain of TYK2, thereby inhibiting downstream signaling pathways. Envudeucitinibum hydrochloride is used for research on plaque psoriasis, systemic lupus erythematosus, and other immune-mediated diseases.
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Methyl ergonovine-d5 maleate salt
0 ImagesCat. No.: HY-W740163Methyl ergonovine-d5 maleate salt is the deuterium labeled Methyl ergonovine maleate salt.
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3-Methyl-2-buten-1-yl Thiolacetate-d6
0 ImagesCat. No.: HY-W777067CAS No.: 1189502-84-83-Methyl-2-buten-1-yl Thiolacetate-d6 is the deuterium labeled 3-Methyl-2-buten-1-yl Thiolacetate(3-Methyl-2-buten-1-thiol precursor) (HY-W777066).
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Acotiamide-d6 hydrochloride
0 ImagesCat. No.: HY-121467ASSynonyms: Z-338-d6 hydrochloride; YM443-d6 hydrochlorideAcotiamide-d6 (hydrochloride) is deuterium labeled Acotiamide (hydrochloride).
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Oxaprozin-d10
0 ImagesCat. No.: HY-W709448Synonyms: Oxaprozinum-d10; Wy21743-d10Oxaprozin-d10 (Oxaprozinum-d10; Wy21743-d10) is the deuterium labeled Oxaprozin (HY-B0808). Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.
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Choline-d9 bromide
0 ImagesCat. No.: HY-W127656S2CAS No.: 285979-71-7Choline-d9 (bromide) is the deuterium labeled Choline bromide.
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Nemonoxacin-13C,d3
0 ImagesCat. No.: HY-14956S3Synonyms: TG-873870-13C,d3Nemonoxacin-13C,d3 (TG-873870-13C,d3) is the deuterium and 13C-labeled Nemonoxacin (HY-14956). Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia.
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Veratryl alcohol-13C
0 ImagesCat. No.: HY-W738271CAS No.: 91384-88-2Synonyms: 3,4-Dimethoxybenzyl alcohol-13CVeratryl alcohol-13C (3,4-Dimethoxybenzyl alcohol-13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy.
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5b-Dihydrocortisol 21-O-(1-ethoxy ethyl) ether-d6
0 ImagesCat. No.: HY-W7458905b-Dihydrocortisol 21-O-(1-ethoxy ethyl) ether-d6 is the deuterium labeled 5b-Dihydrocortisol 21-O-(1-ethoxy ethyl) ether.
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rac 2-(tert-Butyldimethylsilyloxy) Ibuprofen-d6
0 ImagesCat. No.: HY-W704952CAS No.: 2714421-43-7rac 2-(tert-Butyldimethylsilyloxy) Ibuprofen-d6 is the deuterium labeled rac 2-(tert-Butyldimethylsilyloxy) Ibuprofen.
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9(S)-HODE-13C18
0 ImagesCat. No.: HY-113455S1Synonyms: Alpha-dimorphecolic acid-13C189(S)-HODE-13C18 ((+)-α-Dimophecolic acid-13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO.
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PACAP (1-38), human, ovine, rat-13C5,15N TFA
0 ImagesCat. No.: HY-P0221SSynonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38-13C5,15N TFAPACAP (1-38), human, ovine, rat-13C5,15N (Pituitary Adenylate Cyclase Activating Polypeptide 38-13C5,15N) TFA is the 13C, 15N-labeled PACAP (1-38), human, ovine, rat (TFA) (HY-P0221A). PACAP (1-38), human, ovine, rat TFA is a PAC1 receptor agonist. PACAP (1-38), human, ovine, rat TFA binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. PACAP (1-38), human, ovine, rat TFA increases the α-secretase activity. PACAP (1-38), human, ovine, rat TFA elevates cytosolic Ca2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP (1-38), human, ovine, rat TFA demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP (1-38), human, ovine, rat TFA can be used for neurotrophic and neuroprotective research.
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24-Nor ursodeoxycholic acid acyl-b-D-glucuronide-d5
0 ImagesCat. No.: HY-W75994724-Nor ursodeoxycholic acid-d5 acyl-b-D-glucuronide is the deuterium labeled 24-Nor ursodeoxycholic acid-d5 acyl-b-D-glucuronide (HY-W759947).
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Nicardipine-d4 hydrochloride
0 ImagesCat. No.: HY-12515AS2Synonyms: YC-93-d4Nicardipine-d4 hydrochloride is deuterated labeled Nicardipine hydrochloride (HY-12515A). Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure.
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2,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5
0 ImagesCat. No.: HY-151081SCAS No.: 1219804-50-82,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,5-Dichlorobiphenyl.
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6-(Methyl-d3)picolinaldehyde
0 ImagesCat. No.: HY-W705329CAS No.: 2712189-02-96-(Methyl-d3)picolinaldehyde is the deuterium labeled 6-Methyl-2-pyridinecarboxaldehyde (HY-W007849).
