2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. NADPH Oxidase
  5. NADPH Oxidase Substrate

NADPH Oxidase Substrate

NADPH Oxidase Isoform Comparison

NADPH Oxidase Substrates (2):

Cat. No. Product Name Effect Purity
  • HY-113449
    Ubiquinone-1
    		Substrate 99.0%
    Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166).
  • HY-117806
    TSR-011-isomer
    		Substrate
    TSR-011-isomer is an isomer of Belizatinib (HY-17603), a ALK inhibitor with an IC50 of 6 nM. TSR-011-isomer acts as a substrate for metabolic hydrolysis and NADPH-dependent metabolism. TSR-011-isomer undergoes enzymatic hydrolysis in mouse plasma and NADPH-dependent metabolism in mouse liver microsomes, thereby supporting clearance processes. TSR-011-isomer can be used in studies related to ALK-driven cancers.