Urocortin, human
Based on 1 Customer Validation
Urocortin, human, a 40-aa neuropeptide, acts as an agonist of endogenous CRF receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 176591-49-4
- Formula: C204H337N63O64
- Molecular Weight:4696.24
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-P0086
Corticotropin-releasing factor (human)
-
HY-P1752
Urocortin II, human
-
HY-P0257
Astressin
-
HY-P1296
Urocortin, rat
-
HY-14130
CP 376395
-
HY-103377
Antalarmin hydrochloride
-
HY-12129
CP 154526 hydrochloride
-
HY-P1294
α-Helical CRF(9-41)
-
HY-14875
Verucerfont
-
HY-P0276
GIP, human
-
HY-12127
Pexacerfont
-
HY-124475
Antalarmin
Biological Activity
Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)[1]
Urocortin, human is an agonist of CRF receptor, with Kis of 0.4, 0.3, and 0.5 nM for human CRF1, rat CRF2α and mouse CRF2β receptors in cell assay, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 176591-49-4
-
Appearance Solid
-
Molecular Weight 4696.24
-
Formula C204H337N63O64
-
Color White to off-white
-
Synonyms
Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I
-
Sequence
Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
-
Sequence Shortening
DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
1 M Acetic acid : 100 mg/mL (21.29 mM; Need ultrasonic)
DMSO : 2 mg/mL (0.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (285 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M Acetic acid | 1 mM | 0.2129 mL | 1.0647 mL | 2.1294 mL | 5.3234 mL |
| 5 mM | 0.0426 mL | 0.2129 mL | 0.4259 mL | 1.0647 mL | |
| 10 mM | 0.0213 mL | 0.1065 mL | 0.2129 mL | 0.5323 mL | |
| 15 mM | 0.0142 mL | 0.0710 mL | 0.1420 mL | 0.3549 mL | |
| 20 mM | 0.0106 mL | 0.0532 mL | 0.1065 mL | 0.2662 mL |
Urocortin, human Related Classifications
HY-P1295 Related Classifications
Powered by Bioz