A-61603 (free base）
A-61603 free base is a potent adrenergic receptor agonist. A-61603 free base reduces carotid artery conductance in anesthetized pigs mediated by α1 and α2 adrenergic receptors (pEC50=7.25). A-61603 free base can be used as a probe to study adrenergic function.
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- CAS No.: 750531-54-5
- Formula: C14H19N3O3S
- Molecular Weight:309.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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All Adrenergic Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 750531-54-5
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Molecular Weight 309.38
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Formula C14H19N3O3S
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SMILES
CS(=O)(NC1=C2CCCC(C2=CC=C1O)C3=NCCN3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Knepper S M, et al. A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype[J]. Journal of Pharmacology and Experimental Therapeutics, 1995, 274(1): 97-103. [Content Brief]
[2]. Mehrotra S, et al. A61603‐Induced Contractions of the Porcine Meningeal Artery Are Mediated by α1‐and α2‐Adrenoceptors[J]. Basic & clinical pharmacology & toxicology, 2007, 100(4): 279-285. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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