A-70874
A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4). A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain). A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor.
For research use only. We do not sell to patients.
- CAS No.: 131449-37-1
- Formula: C45H55N7O10
- Molecular Weight:853.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 131449-37-1
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Molecular Weight 853.96
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Formula C45H55N7O10
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SMILES
NC([C@H](CC1=CC=CC=C1)N(C)C([C@H](CC(O)=O)NC([C@H](CCCCNC(/C=C/C2=CC=C(O)C=C2)=O)NC([C@@H](NC(OC(C)(C)C)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-70874 Related Classifications
HY-129516 Related Classifications
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