AAK1-IN-10
AAK1-IN-10 (Compound 1-2) is an AAK1 inhibitor. AAK1-IN-10 has significant AAK1 enzyme inhibitory activity (IC50: 9.62 nM). AAK1-IN-10 mainly exerts its effects by inhibiting the activity of connexin-associated kinase 1 (AAK1). AAK1-IN-10 has low cardiotoxicity (IC50 = 13.7 μM). AAK1-IN-10 can be used in the study of diabetic neuropathy and postherpetic pain.
For research use only. We do not sell to patients.
- CAS No.: 3083494-45-2
- Formula: C19H23F4N3O3
- Molecular Weight:417.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3083494-45-2
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Molecular Weight 417.40
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Formula C19H23F4N3O3
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SMILES
FC(F)C1=NC=CC(C2=CC=C(OC[C@](N)(C)C[C@](O)(C)CO)C(C(F)F)=N2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)