Sabizabulin hydrochloride
Based on 4 publication(s) in Google Scholar
Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects.
For research use only. We do not sell to patients.
- CAS No.: 2635953-17-0
- Formula: C21H20ClN3O4
- Molecular Weight:413.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Sabizabulin hydrochloride
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 2635953-17-0
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Molecular Weight 413.85
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Formula C21H20ClN3O4
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SMILES
O=C(C1=CN=C(C2=CNC3=C2C=CC=C3)N1)C4=CC(OC)=C(C(OC)=C4)OC.Cl
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Synonyms
VERU-111 hydrochloride; ABI-231 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
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Mol Cancer Ther
RGN6024 is a brain-penetrant, small molecule tubulin destabilizer for the treatment of glioblastoma. [Abstract]2025 Aug 1;24(8):1129-1144. PMID: 40397474 -
Biomedicines
Novel Brain-Penetrant, Small-Molecule Tubulin Destabilizers for the Treatment of Glioblastoma. [Abstract]2024 Feb 9;12(2):406. PMID: 38398008 -
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Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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