Ac-Arg-Gly-Lys(Ac)-AMC
Based on 1 Customer Validation
Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 660846-97-9
- Formula: C28H40N8O7
- Molecular Weight:600.67
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Following initial inhibition of HDACs, the peptide substrate Ac-Arg-Gly-Lys-AMC is added to the reaction tubes for next 30?min and finally the stop solution stopped the reaction mediated by HDAC enzymes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 660846-97-9
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Appearance Solid
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Molecular Weight 600.67
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Formula C28H40N8O7
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Color White to off-white
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Sequence Shortening
Ac-RG{K(Ac)}-AMC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
H2O : ≥ 50 mg/mL (83.24 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6648 mL | 8.3240 mL | 16.6481 mL | 41.6202 mL |
| 5 mM | 0.3330 mL | 1.6648 mL | 3.3296 mL | 8.3240 mL | |
| 10 mM | 0.1665 mL | 0.8324 mL | 1.6648 mL | 4.1620 mL | |
| 15 mM | 0.1110 mL | 0.5549 mL | 1.1099 mL | 2.7747 mL | |
| 20 mM | 0.0832 mL | 0.4162 mL | 0.8324 mL | 2.0810 mL | |
| 25 mM | 0.0666 mL | 0.3330 mL | 0.6659 mL | 1.6648 mL | |
| 30 mM | 0.0555 mL | 0.2775 mL | 0.5549 mL | 1.3873 mL | |
| 40 mM | 0.0416 mL | 0.2081 mL | 0.4162 mL | 1.0405 mL | |
| 50 mM | 0.0333 mL | 0.1665 mL | 0.3330 mL | 0.8324 mL | |
| 60 mM | 0.0277 mL | 0.1387 mL | 0.2775 mL | 0.6937 mL | |
| 80 mM | 0.0208 mL | 0.1041 mL | 0.2081 mL | 0.5203 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Ac-Arg-Gly-Lys(Ac)-AMC Related Classifications
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