AChE-IN-69
AChE-IN-69 (compound 7o) is a potent AChE inhibitor with an IC50 value of 1.67 µM. AChE-IN-69 has the potential for the research of Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 2755986-33-3
- Formula: C16H12F3N3OS
- Molecular Weight:351.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE 1.67 μM (IC50) |
In Vitro
AChE-IN-69 (compound 7o) binds to the active center of AChE, which hindered the substrate acetylthiocholine iodide (ATCI) from binding to the enzyme, resulting in a decrease in enzyme activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2755986-33-3
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Molecular Weight 351.35
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Formula C16H12F3N3OS
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SMILES
O=C1C2=C(SC(C3=CC=C(C(F)(F)F)C=C3)=N2)N=C4N1CCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-69 Related Classifications
HY-159116 Related Classifications
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